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Showing results 1 to 12 of 12.
Issue DateTitleAuthor(s)TypeAccess
May-2011Distinct regulation of p53-mediated apoptosis by protein kinase calpha, delta, epsilon and zeta: evidence in yeast for transcription-dependent and -independent p53 apoptotic mechanismsCoutinho, Isabel; Pereira, Clara; Pereira, Gil, et al.ArticleOpen access
2021Mechanism of Antifungal Activity by 5-Aminoimidazole-4-Carbohydrazonamide Derivatives against Candida albicans and Candida kruseiCerqueira, Fátima; Maia, Marta; Gabriel, Carla, et al.ArticleOpen access
May-2011Modulation of Bax by Protein Kinase C in yeastSilva, Rui D.; Manon, Stéphen; Gonçalves, Jorge, et al.AbstractOpen access
2011Modulation of bax mitochondrial insertion and induced cell death in yeast by mammalian protein kinase calphaSilva, Rui D.; Manon, Stéphen; Gonçalves, Jorge, et al.ArticleOpen access
13-Apr-2021A selective p53 activator and anticancer agent to improve colorectal cancer therapyRamos, Helena; Soares, Maria I. L.; Silva, Joana, et al.ArticleOpen access
15-Mar-2021Semi-synthesis of small molecules of aminocarbazoles: tumor growth inhibition and potential impact on p53Long, Solida; Loureiro, Joana B.; Carvalho, Carla, et al.ArticleOpen access
Jan-2020SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutationsGomes, A. S.; Ramos, Helena; Gomes, S., et al.ArticleOpen access
10-Aug-2019SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular CarcinomaGomes, Sara; Bosco, Bartolomeo; Loureiro, Joana B., et al.ArticleOpen access
1-Apr-2021Targeting p53 for melanoma treatment: counteracting tumour proliferation, dissemination and therapeutic resistanceLoureiro, Joana B.; Raimundo, Liliana; Calheiros, Juliana, et al.ArticleOpen access
2018The Crystal Structure of the R280K Mutant of Human p53 Explains the Loss of DNA BindingGomes, Ana Sara; Trovão, Filipa; Andrade Pinheiro, Benedita, et al.ArticleOpen access
2011The importance of humanized yeast to better understand the role of Bcl-2 family in apoptosis : finding of novel therapeutic opportunitiesSilva, Rui D.; Manon, Stéphen; Gonçalves, Jorge, et al.ArticleOpen access
Feb-2017Uncovering the binding of the anticancer small molecule SLMP53-1 to mutant p53R280KGomes, A. S.; Gomes, S.; Soares, Joana, et al.AbstractOpen access