Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/13779
Título: | “In situ” corneal and contact lens thickness changes with high resolution OCT |
Autor(es): | González-Méijome, José Manuel Cerviño, Alejandro Peixoto-de-Matos, S. C. Madrid-Costa, David Jorge, Jorge Ferrer-Blasco, Teresa |
Palavras-chave: | Coherence tomography Cornea OCT stromal thickness epithelial thickness edema contact lenses |
Data: | 2012 |
Editora: | Lippincott, Williams & Wilkins |
Revista: | Cornea |
Resumo(s): | Purpose: To show the utility of high resolution spectral domain optical coherence tomography (HR SOCT) for the in situ evaluation of epithelial, stromal and contact lens (CL) thickness changes under closed-eye conditions without lens removal. Settings: Clinical and Experimental Optometry Research Lab, University of Minho, Portugal. Methods: Eight young healthy patients wore a thick soft CL during 90 minutes under closed-eye conditions and measures of epithelial and stromal corneal thickness were obtained at regular intervals using a HR SOCT (Copernicus HR, Optopol Tech. SA, Poland). Results: Minimal changes in epithelial thickness were detected with a transient statistically significant increase in epithelial thickness in the fellow control eye 30 minutes after insertion (p=0.028). A significant and progressive increase in stromal thickness up to 8% after 90 minutes of lens wear was observed at a constant rate of 2.5% 50 every 30 minutes, being statistically significant in all observations (p<0.001). Fellow control eye also showed a significant increase in stromal thickness at a much lower rate of 0.5% every 30 minutes. Lens thickness decreased significantly by 2% after 90 minutes of lens wear under closed eye conditions (p<0.001). Individual analysis showed that all eyes displayed stromal swelling, while only half of them showed epithelial swelling. Conclusion: Increase in stromal thickness and a slight decrease in lens thickness were observed in response to a hypoxic stimulus under closed eye conditions. High resolution spectral domain HR SOCT is a powerful tool to investigate in vivo the physiological interactions between cornea and contact lenses. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/13779 |
DOI: | 10.1097/ICO.0b013e31823f0905 |
ISSN: | 0277-3740 |
Versão da editora: | http://journals.lww.com/corneajrnl/pages/default.aspx |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDF - OCV - Artigos/Papers (with refereeing) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
5.5.65b. GONZALEZ-MEIJOME_11_CORNEA (SOCT Epithelial Stromal CL Thickness Changes Overnight).pdf | 1,04 MB | Adobe PDF | Ver/Abrir |