Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/20785
Título: | Nanostructured thin coatings from chitosan and an elastin-like recombinamer with acute stimuli-responsive behavior |
Autor(es): | Costa, Rui R. Ribeiro, Artur J. Rodríguez-Cabello, José Carlos Mano, J. F. |
Palavras-chave: | Surface engineering Layer-by-layer Biomaterials Recombinant polymers |
Data: | 2013 |
Editora: | Trans Tech Publications |
Revista: | Materials Science Forum |
Resumo(s): | In the present work, chitosan (CHI) and elastin-like recombinamers (ELRs) were used to conceive nanostructured thin films driven by sequential electrostatic layer-by-layer (LbL), a simple and versatile technique that discards the use of harmful reagents. Two similar ELRs were engineered to contain negatively charged aminoacids and organized and a single monoblock or a triblock. The buildup of the films was monitored in real time using a quartz-crystal microbalance with dissipation monitoring (QCM-D). Wettability transitions were observed from a moderate hydrophobic surface to an extremely wettable upon increasing the temperature to 50 ºC, accompanied by topography changes at the nanoscale as assessed by atomic force microscopy (AFM). Furthermore, the dependence on time for the surface molecular rearrangement was studied for the films with each ELR. The potential of this technology may stimulate the development of devices and biomaterials for biomedical applications in the near future, such as surfaces with tunable and patterned cell adhesion, while the use of ELRs will allow developing polypeptides with biological significance. |
Tipo: | Artigo em ata de conferência |
Descrição: | Publicado em: Materials Science Forum, vols. 730-732; Online available since 2012/Nov/12 |
URI: | https://hdl.handle.net/1822/20785 |
DOI: | 10.4028/www.scientific.net/MSF.730-732.32 |
ISSN: | 0255-5476 |
Versão da editora: | http://www.scientific.net/MSF.730-732.32 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
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Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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MSF.730-732.32.pdf | Documento principal | 740,28 kB | Adobe PDF | Ver/Abrir |