Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/26698
Título: | Synthesis and photophysical studies of new pyrenylamino acids |
Autor(es): | Pereira, Goreti Castanheira, Elisabete M. S. Schellenberg, Peter Michael Belsley, M. Ferreira, Paula M. T. Monteiro, Luís S. |
Palavras-chave: | beta-bromodehydroalanines Pyrenylamino acids Photophysical studies Fluorescent probes β-Bromodehydroalanines |
Data: | Dez-2013 |
Editora: | Elsevier |
Revista: | Tetrahedron |
Resumo(s): | Two new pyrenylamino acid derivatives were synthesized from beta-bromodehydroalanine derivatives in good yields using addition and elimination reactions. The photophysical properties of the two new pyrenylamino acids were studied in several solvents. Steady-state and time-resolved fluorescence measurements revealed that the bipyrenylamino acid undergoes excimer formation, this process being solvent dependent. Rate constants for excimer formation and dissociation were calculated. The monopyrenylamino acid exhibits a photophysical behavior similar to that of pyrene, including the sensitivity to solvent polarity. The results point to a potential use of these new pyrenyl derivatives as fluorescent probes for peptides and proteins. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/26698 |
DOI: | 10.1016/j.tet.2013.10.035 |
ISSN: | 0040-4020 |
Versão da editora: | http://www.sciencedirect.com |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDF - FAMO - Artigos/Papers (with refereeing) CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
2013-Pyrenylamino acids_Tetrahedron.pdf | Documento principal | 914,9 kB | Adobe PDF | Ver/Abrir |
Supplementary data_Tet2013.pdf | Informação suplementar | 139,87 kB | Adobe PDF | Ver/Abrir |