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TitleAdhesion of Pseudomonas aeruginosa and Staphylococcus epidermidis to silicone-hydrogel contact lenses
Author(s)Henriques, Mariana
Sousa, Cláudia Miriam Pereira
Lira, Madalena
Real Oliveira, M. Elisabete C.D.
Oliveira, Rosário
Azeredo, Joana
KeywordsSilicone–hydrogel contact lenses
Bacterial adhesion
P. aeruginosa
S. epidermidis
Issue dateJun-2005
PublisherAmerican Academy of Optometry (AAOPT)
JournalOptometry and vision science
Citation"Optometry and vision science". ISSN 1040-5488. 82:6 (Jun. 2005) 446-450.
Abstract(s)Purpose. The purpose of this study is to compare the adhesion capabilities of the most important etiologic agents of microbial ocular infection to the recently available silicone– hydrogel lenses with those to a conventional hydrogel lens. Methods. In vitro static adhesion assays of Pseudomonas aeruginosa 10,145, Staphylococcus epidermidis 9142 (biofilm-positive), and 12,228 (biofilm-negative) to two extended-wear silicone– hydrogel lenses (balafilcon A and lotrafilcon A), a daily wear silicone– hydrogel lens (galyfilcon A) and a conventional hydrogel (etafilcon A) were performed. To interpret the adhesion results, lens surface relative hydrophobicity was assessed by water contact angle measurements. Results. P. aeruginosa and S. epidermidis 9142 exhibited greater adhesion capabilities to the extended wear silicone– hydrogel lenses than to the daily wear silicone– and conventional hydrogel lenses (p < 0.05). No statistical differences were found between the adhesion extent of these strains to galyfilcon A and etafilcon A. The biofilm negative strain of S. epidermidis adhered in larger extents to the silicone– hydrogel lenses than to the conventional hydrogel (p < 0.05), but in much lower amounts than the biofilm-positive strain. The water contact angle measurements revealed that the extended wear silicone– hydrogel lenses are hydrophobic, whereas the daily wear silicone– and conventional hydrogel lenses are hydrophilic. Conclusions. As a result of their hydrophobicity, the extended wear silicone– hydrogel lenses (lotrafilcon A and balafilcon A) may carry higher risk of microbial contamination than both the hydrophilic daily wear silicone– hydrogel lens, galyfilcon A and the conventional hydrogel lens, etafilcon A.
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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