Effect of melanomal proteins on sepia melanin assembly

doi:10.1080/00222348.2015.1103430

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/38359

Título:	Effect of melanomal proteins on sepia melanin assembly
Autor(es):	Srisuk, Pathomthat Correlo, V. M. Leonor, I. B. Palladino, Pasquale Reis, R. L.
Palavras-chave:	Amyloid fibrils Atomic force microscopy Cephalopod ink Scanning electron microscopy Scanning transmission electron microscopy Sepia melanin self-assembly
Data:	Out-2015
Editora:	Taylor and Francis
Revista:	Journal of Macromolecular Science Part B Physics
Citação:	Srisuk P., Correlo V. M., Leonor I. B., Palladino P., Reis R. L. Effect of Melanomal Proteins on Sepia Melanin Assembly, Journal of Macromolecular Science, Part B: Physics, doi:10.1080/00222348.2015.1103430, 2015
Resumo(s):	Melanins are phenol-based pigments with the potential for widespread applications including bioelectronics and tissue engineering. The concentration-dependent structural transition of sepia melanin in water is analyzed. This biopolymer at high concentration gives the well-known nanospheres, whereas sample dilution gives unforeseen nanofibres exhibiting the structural features of mature amyloid fibrils. We propose a mechanism of pigment self-assembly dependent on the interaction of residual melanosomal protein(s) with eumelanin heteropolymer. Our results contribute to understanding the peculiar physico-chemical properties of this ubiquitous pigment
Tipo:	Artigo
Descrição:	Accepted manuscript
URI:	https://hdl.handle.net/1822/38359
DOI:	10.1080/00222348.2015.1103430
ISSN:	0022-2348 1525-609X
Versão da editora:	http://www.tandfonline.com/doi/abs/10.1080/00222348.2015.1103430
Arbitragem científica:	yes
Acesso:	Acesso aberto
Aparece nas coleções:	3B’s - Artigos em revistas/Papers in scientific journals