Please use this identifier to cite or link to this item: https://hdl.handle.net/1822/39110

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dc.contributor.authorMaia, M.por
dc.contributor.authorGabriel, C.por
dc.contributor.authorCravo, S.por
dc.contributor.authorDias, Alicepor
dc.contributor.authorRibeiro, A.por
dc.contributor.authorProença, M. Fernanda R. P.por
dc.contributor.authorCerqueira, F.por
dc.contributor.authorPinto, E.por
dc.date.accessioned2015-12-21T18:49:49Z-
dc.date.issued2015-12-01-
dc.identifier.urihttps://hdl.handle.net/1822/39110-
dc.description.abstract[Excerpt] The incidence of fungal infections has greatly increased in patients under sustained immunosuppression with considerable risk associated. Difficulties regarding prompt diagnosis and the limited therapeutic options dictate high mortality rates. Available antifungals display substantial toxicity, a predictable consequence of the cellular structure of the organisms involved, reduced spectrum of activity, and drug interactions. Our group had previously identified three (Z)-5-amino-N'-aryl-1-methyl-1H-imidazole-4-carbohydrazonamides 1 [aryl= phenyl (1a), 4-fluorophenyl (1b), 3fluorophenyl (1c)] as potent antifungal agents.1 (...)-
dc.description.sponsorshipFCT (NMR portuguese network); FCT and FEDER-COMPETE-QREN-EU [CEQUIMED-Pest-OE/SAU/UI4040/2014;Pest-C/QUI/UI0686/2011 (FCOMP-01-0124-FEDER-022716)]; Strategic Funding UID/Multi/04423/2013 through national funds provided by FCT and European Regional Development Fund (ERDF), in the framework of the programme PT2020por
dc.language.isoengpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/135933/PTpor
dc.relationPest-C/QUI/UI0686/2011por
dc.rightsrestrictedAccesspor
dc.subjectQuímica Orgânicapor
dc.subjectQuímica Terapêuticapor
dc.titleAntifungal action of three (Z)-5-amino-N'-aryl-1-methyl-1H-imidazole-4-carbohydrazonamidespor
dc.typeconferenceAbstract-
dc.peerreviewedyespor
sdum.publicationstatuspublishedpor
oaire.citationConferenceDate1 – 3 Dez. 2015por
sdum.event.typecongresspor
oaire.citationConferencePlacePorto, Portugalpor
oaire.citationTitleCongresso de Química Orgânica e Terapêuticapor
dc.subject.fosCiências Naturais::Ciências Químicaspor
Appears in Collections:CDQuim - Comunicações e Proceedings

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