Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/39770
Título: | Goblet cell density association with tear function and ocular surface physiology |
Autor(es): | Sapkota, Kishor Franco, Sandra Sampaio, Paula Lira, Madalena |
Palavras-chave: | Goblet cell density Schirmer score Tear break-up time Bulbar redness Corneal staining |
Data: | Ago-2015 |
Editora: | Elsevier |
Revista: | Contact Lens and Anterior Eye |
Citação: | Sapkota, K., Franco, S., Sampaio, P., & Lira, M. (2015). Goblet cell density association with tear function and ocular surface physiology. Contact Lens & Anterior Eye, 38(4), 240-244. doi: 10.1016/j.clae.2015.01.016 |
Resumo(s): | Purpose: To determine the relationship of goblet cell density (GCD) with tear function and ocular surface physiology. Methods: This was a cross-sectional study conducted in 35 asymptomatic subjects with mean age 23.8±3.6 years. Tear film assessment, conjunctiva and cornea examination were done in each subject. Conjunctival impression cytology was performed by applying Nitrocellulose Millipore MFTM-Membrane filter over the superior bulbar conjunctiva. The filter paper was than fixed with 96% ethanol and stained with Periodic Acid Schiff, Hematoxylin and Eosin. GCD was determined by optical microscopy. Relation between GCD and Schirmer score, tear break-up time (TBUT), bulbar redness, limbal redness and corneal staining was determined. Results: The mean GCD was 151±122 cells/mm2. GCD was found higher in eyes with higher Schirmer score but it was not significant (p = 0.75). There was a significant relationship ofGCDwith TBUT (p = 0.042). GCD was not correlated with bulbar redness (p = 0.126), and limbal redness (p = 0.054) as well as corneal staining (p = 0.079). No relationship of GCD with age and gender of the subjects (p > 0.05) was observed. Conclusion: GCD was found correlated with TBUT but no significant correlation was found with the aqueous portion of the tear, limbal as well as bulbar redness and corneal staining. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/39770 |
DOI: | 10.1016/j.clae.2015.01.016 |
ISSN: | 1367-0484 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CDF - OCV - Artigos/Papers (with refereeing) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Goblet cell density.pdf Acesso restrito! | 1,07 MB | Adobe PDF | Ver/Abrir |