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TitleGene therapy, growth factors, mesenchymal cells, new trends and future perspectives
Author(s)Zaffagnini, Stefano
Cucchiarini, Magali
de Girolamo, Laura
Angele, Peter
Pereira, H.
Reis, R. L.
Madry, Henning
Orfei, Carlotta Perucca
Zellner, Johannes
Filardo, Giuseppe
KeywordsGene therapy
Growth factors
Mesenchymal Cells
Issue dateMar-2016
PublisherSpringer Verlag
CitationZaffagnini S., Cucchiarini M., de Girolamo L., Angele P., Pereira H., Reis R. L., Madry H., Orfei P. C., Zellner J., Filardo G. Gene Therapy, Growth Factors, Mesenchymal Cells, New Trends and Future Perspective, Surgery of the Meniscus, pp. 559-575, doi:10.1007/978-3-662-49188-1_58, 2016
Abstract(s)Meniscal tears are common, prevalent intra-articular knee injury and the most frequent cause of orthopedic surgical procedures [1], being a significant risk factor for the development of osteoarthritis (OA) [2]. As widely documented in the previous chapters, tears in the peripheral (vascularized) portion of the meniscus can be repaired using a variety of operative procedures, while those in the central (avascular) area have a poorer healing capacity. Reconstruction of a torn meniscus in this location is challenging, and the long-term effect of allografts on the progression of OA remains uncertain [3].
TypeBook part
Publisher version
AccessRestricted access (UMinho)
Appears in Collections:3B’s - Capítulos de Livros/Book Chapters

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