Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/49709

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dc.contributor.authorMorais, Pedro André Gonçalvespor
dc.contributor.authorTavares, João Manuel R. S.por
dc.contributor.authorQueirós, Sandro Filipe Monteiropor
dc.contributor.authorVeloso, Fernandopor
dc.contributor.authorD’hooge, Janpor
dc.contributor.authorVilaça, João L.por
dc.date.accessioned2018-01-25T14:23:34Z-
dc.date.issued2017-11-30-
dc.identifier.citationMorais, P., Tavares, J. M. R., Queirós, S., Veloso, F., D'hooge, J., & Vilaça, J. L. (2017). Development of a patient‐specific atrial phantom model for planning and training of inter‐atrial interventions. Medical physics, 44(11), 5638-5649por
dc.identifier.issn0094-2405-
dc.identifier.urihttps://hdl.handle.net/1822/49709-
dc.descriptionArticle is accepted for publicationpor
dc.description.abstractBackgroundSeveral authors have presented cardiac phantoms to mimic the particularities of the heart, making it suitable for medical training and surgical planning. Although the initial models were mainly focused on the ventricles, personalized phantoms of the atria were recently presented. However, such models are typically rigid, the atrial wall is not realistic and they are not compatible with ultrasound (US), being sub-optimal for planning/training of several interventions. MethodsIn this work, we propose a strategy to construct a patient-specific atrial model. Specifically, the target anatomy is generated using a computed tomography (CT) dataset and then constructed using a mold-cast approach. An accurate representation of the inter-atrial wall (IAS) was ensured during the model generation, allowing its application for IAS interventions. Two phantoms were constructed using different flexible materials (silicone and polyvinyl alcohol cryogel, PVA-C), which were then compared to assess their appropriateness for US acquisition and for the generation of complex anatomies. ResultsTwo experiments were set up to validate the proposed methodology. First, the accuracy of the manufacturing approach was assessed through the comparison between a post-production CT and the virtual references. The results proved that the silicone-based model was more accurate than the PVA-C-based one, with an error of 1.680.79, 1.36 +/- 0.94, 1.45 +/- 0.77mm for the left (LA) and right atria (RA) and IAS, respectively. Second, an US acquisition of each model was performed and the obtained images quantitatively and qualitatively assessed. Both models showed a similar performance in terms of visual evaluation, with an easy detection of the LA, RA, and the IAS. Furthermore, a moderate accuracy was obtained between the atrial surfaces extracted from the US and the ideal reference, and again a superior performance of the silicone-based model against the PVA-C phantom was observed. ConclusionsThe proposed strategy proved to be accurate and feasible for the correct generation of complex personalized atrial models.por
dc.description.sponsorshipThe authors acknowledge "Fundacao para a Ciencia e a Tecnologia" (FCT), in Portugal, and the European Social Found, European Union, for funding support through the "Programa Operacional Capital Humano" (POCH) in the scope of the PhD grants SFRH/BD/95438/2013 (P. Morais) and SFRH/BD/93443/2013 (S. Queiros).Authors gratefully acknowledge the funding of Projects NORTE-01-0145-FEDER-000013 and NORTE-01-0145-FEDER-000022, cofinanced by "Programa Operacional Regional do Norte" (NORTE2020), through "Fundo Europeu de Desenvolvimento Regional" (FEDER).por
dc.language.isoengpor
dc.publisherWileypor
dc.rightsopenAccess-
dc.subjectPatient - specific phantom modelspor
dc.subjectCardiac atriapor
dc.subjectInter - atrial septal wallpor
dc.subject3D - printingpor
dc.subjectUltrasound compatible phantom modelpor
dc.titleDevelopment of a patient-specific atrial phantom model for planning and training of inter-atrial interventionspor
dc.typearticlepor
dc.peerreviewedyespor
dc.relation.publisherversionhttp://onlinelibrary.wiley.com/doi/10.1002/mp.12559/fullpor
oaire.citationStartPage5638por
oaire.citationEndPage5649por
oaire.citationIssue11por
oaire.citationVolume44por
dc.date.updated2018-01-08T16:19:24Z-
dc.identifier.doi10.1002/mp.12559por
dc.identifier.pmid28887857por
dc.subject.fosCiências Médicas::Medicina Básicapor
dc.description.publicationversioninfo:eu-repo/semantics/publishedVersionpor
dc.subject.wosScience & Technologypor
sdum.journalMedical Physicspor
Aparece nas coleções:ICVS - Artigos em revistas internacionais / Papers in international journals

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