Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/51414
Título: | Bone turnover markers in sheep and goat: a review of the scientific literature |
Autor(es): | Camassa, José A. Diogo, Camila C. Sousa, Cristina P. Azevedo, Jorge T. Viegas, Carlos A. Reis, R. L. Dourado, N. Dias, Isabel R. |
Palavras-chave: | Bone formation markers Bone resorption markers Bone metabolism Small ruminants |
Data: | Mar-2017 |
Editora: | Academia Brasileira de Ciências |
Revista: | Annals of the Brazilian Academy of Sciences |
Citação: | Camassa J. A., Diogo C. C., Sousa C. P., Azevedo J. T., Viegas C. A., Reis R. L., Dourado N., Dias I. R. Bone turnover markers in sheep and goat: A review of the scientific literature, Annals of the Brazilian Academy of Sciences, Vol. 89, Issue 1, pp. 231-245, doi:10.1590/0001-3765201720160407, 2017 |
Resumo(s): | Bone turnover markers (BTMs) are product of bone cell activity and are generally divided in bone formation and bone resorption markers. The purpose of this review was to structure the available information on the use of BTMs in studies on small ruminants, especially for monitoring their variations related to diet, exercise, gestation and metabolic lactation state, circadian and seasonal variations, and also during skeletal growth. Pre-clinical and translational studies using BTMs with sheep and goats as animal models in orthopaedic research studies to help in the evaluation of the fracture healing process and osteoporosis research are also described in this review. The available information from the reviewed studies was systematically organized in order to highlight the most promising BTMs in small ruminant research, as well as provide a wide view of the use of sheep and goat as animal models in orthopaedic research, type of markers and commercial assay kits with cross-reactivity in sheep and goat, method of sample and storage of serum and urine for bone turnover markers determination and the usefulness and limitations of bone turnover markers in the different studies, therefore an effective tool for researchers that seek answers to different questions while using BTMs in small ruminants. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/51414 |
DOI: | 10.1590/0001-3765201720160407 |
ISSN: | 0001-3765 |
e-ISSN: | 1678-2690 |
Versão da editora: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100231&lng=en&tlng=en |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals DEM - Artigos em revistas de circulação internacional com arbitragem científica |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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19465-IRDias-AnaisAcadBrasCi2017.pdf | 1,21 MB | Adobe PDF | Ver/Abrir |