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TitleComparative genomics of wild type yeast strains unveils important genome diversity
Author(s)Carreto, Laura
Eiriz, Maria F.
Gomes, Ana C.
Pereira, Patrícia M
Schuller, Dorit Elisabeth
Santos, Manuel A. S.
KeywordsComparative Genomic Hybridization
DNA Helicases
DNA, Fungal
Gene Dosage
Genes, Fungal
Genetic Variation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Species Specificity
Genome, Fungal
Issue date4-Nov-2008
PublisherBioMed Central (BMC)
JournalBMC Genomics
Abstract(s)Genome variability generates phenotypic heterogeneity and is of relevance for adaptation to environmental change, but the extent of such variability in natural populations is still poorly understood. For example, selected Saccharomyces cerevisiae strains are variable at the ploidy level, have gene amplifications, changes in chromosome copy number, and gross chromosomal rearrangements. This suggests that genome plasticity provides important genetic diversity upon which natural selection mechanisms can operate.
AccessOpen access
Appears in Collections:DBio - Artigos/Papers

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