Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/59172| Título: | In vitro characterization on the interactions between carboxymethyl-chitosan/poly(amidoamine) dendrimer nanoparticles and neurons/glial cells |
| Autor(es): | Oliveira, Joaquim M. Salgado, A. J. Pirraco, R. P. Pereira, V. H. Fraga, J. S. Marques, A. P. Neves, N. M. Mano, J. F. Reis, R. L. Sousa, Nuno |
| Data: | 2008 |
| Editora: | Mary Ann Liebert Inc. |
| Revista: | Tissue Engineering. Part A |
| Resumo(s): | [Excerpt] Central nervous system associated disorders are a leading cause of disability worldwide. In recent years targeted drug delivery nanoparticle based systems for intracellular application have been put forward has a possible therapeutic route to follow. In this sense the objective of the present report was to characterize and evaluate the possible applicability of recently developed carboxymethylchitosan/poly(amidoamine) (CMC/PAMAM) dendrimer nanoparticles in central nervous system (CNS) cell populations. Atomic force and transmission electron microscopy observations revealed that these nanoparticles possessed a nanosphere-like shape and sizes between 2–123 nm. [...] |
| Tipo: | Resumo em ata de conferência |
| URI: | https://hdl.handle.net/1822/59172 |
| ISSN: | 1937-3341 |
| Arbitragem científica: | yes |
| Acesso: | Acesso aberto |
| Aparece nas coleções: |
Ficheiros deste registo:
| Ficheiro | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| TermisEU_OP153.pdf | 34,02 kB | Adobe PDF | Ver/Abrir |
