Exploring polydopamine-based coating strategies to boost chlorohexidine immobilization for the development of an antimicrobial surface

Abstract

[Excerpt] Introduction Orthopedic implants have been widely used to restore the function of load-bearing joints, reducing pain and improving the life quality of millions of people every year. These devices are, however, prone to microbial infection, which remains a major cause of morbidity and mortality in modern Healthcare. The development of novel approaches to confer the surfaces of orthopedic implants with anti-infective properties is, therefore, in great demand.[...]