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TitleIncorporation of lipid nanosystems containing omega‑3 fatty acids and resveratrol in textile substrates for wound healing and anti‑inflammatory applications
Author(s)Silva, Juliana
Mesquita, Rui
Pinho, Eva Patrícia Paiva Santos
Caldas, Ana
Real Oliveira, M. Elisabete C.D.
Lopes, Carla M.
Lúcio, Marlene
Soares, Graça
KeywordsTextiles lipid nanosystems
Nanostructured lipid carriers (NLCs)
Wound healing
Anti-inflammatory effects
Issue date3-Sep-2019
PublisherSpringer Nature
JournalSN Applied Sciences
CitationSN Applied Sciences (2019) 1:1007 |
Abstract(s)In the present work, lipid nanosystems containing omega-3 fatty acid (nanostructured lipid carriers, NLCs) or omega-3 fatty acid and resveratrol (liposomes) were developed to improve cotton textile substrates as dressings with anti-inflammatory properties for wound healing applications. Lipid nanosystems were incorporated into woven, non-woven and knitted cotton substrates by exhaustion and impregnation. Based on physical–chemical characterization of the textile substrates, the textile structure and type of lipid nanosystems dictated the adsorption efficiency. In the case of NLCs, the woven substrate functionalized by exhaustion had a higher omega-3 release being the most promising for wound dressing application. Whereas for liposomes, the most adequate textile was the cationized knitted fabric functionalized by impregnation, that showed a more prolonged release profile of resveratrol.
Publisher version
AccessOpen access
Appears in Collections:CDF - FAMO - Artigos/Papers (with refereeing)

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