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TitleThe resting-brain of obsessive-compulsive disorder
Author(s)Moreira, Pedro Silva
Marques, Paulo
Magalhães, Ricardo
Esteves, Madalena
Sousa, Nuno
Soares, José Miguel
Morgado, Pedro
KeywordsObsessive-compulsive disorder
Resting-state networks
Issue date30-Aug-2019
JournalPsychiatry Research: Neuroimaging
Abstract(s)Obsessive–compulsive disorder (OCD) is one of the most debilitating psychiatric conditions, having a dramatic impact on patients’ daily living. In this work, we aimed to explore resting-state functional connectivity in OCD patients, using an independent component analysis. Eighty individuals (40 patients and 40 healthy controls) performed a resting state fMRI protocol. OCD patients displayed reduced functional connectivity (FC) in visual and sensorimotor networks. In addition, patients displayed decreased FC between sensory networks and increased FC between default-mode and cerebellar networks.
AccessOpen access
Appears in Collections:ICVS - Artigos em revistas internacionais / Papers in international journals

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