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TitleDevelopment and application of a novel peptide nucleic acid probe for the specific detection of helicobacter pylori in gastric biopsy specimens
Author(s)Guimarães, N.
Azevedo, N. F.
Figueiredo, C.
Keevil, C. W.
Vieira, M. J.
Issue dateSep-2007
PublisherAmerican Society for Microbiology (ASM)
JournalJournal of Clinical Microbiology
Citation"Journal of Clinical Microbiology". ISSN 0095-1137. 45:9 (Sept. 2007) 3089-3094.
Abstract(s)In this work, a fluorescence in situ hybridization (FISH) method for the rapid detection of Helicobacter pylori using a novel peptide nucleic acid (PNA) probe is reported. Laboratory testing with several different bacterial species, including other Helicobacter spp., has shown that this probe is highly specific for H. pylori strains. In addition, the PNA FISH method has been successfully adapted for detection of the pathogen in paraffinembedded gastric biopsy specimens.
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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