Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/72910
Título: | Enhancing reductive cleavage of aromatic carboxamides |
Autor(es): | Ragnarsson, Ulf Grehn, Leif Maia, Hernâni Lopes Silva Monteiro, Luís S. |
Data: | 2001 |
Editora: | American Chemical Society |
Revista: | Organic Letters |
Resumo(s): | [GRAPHICS] A set of aromatic and especially heteroaromatic N-benzyl carboxamides, derived from naphthalene, pyridine, pyrazine, and quinoline, and the corresponding tert-butyl acylcarbamates have been synthesized and studied by cyclic voltammetry with respect to facilitated reduction. The latter undergo regiospecific cleavage of their C(O)-N bonds under very mild reductive conditions with formation of Boc-protected (benzyl)amine in most cases in nearly quantitative yields, Examples of preparative cleavage by controlled potential electrolysis, activated aluminum, and NaBH4 are given. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/72910 |
DOI: | 10.1021/ol010072a |
ISSN: | 1523-7060 |
Versão da editora: | https://doi.org/10.1021/ol010072a |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2001-Organic Letters 2021.pdf | 33,24 kB | Adobe PDF | Ver/Abrir |