Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/72967
Título: | Electrochemical reduction of beta-aryldehydroamino acid derivatives |
Autor(es): | Monteiro, Luís S. Ferreira, Paula M. T. Pereira, G. Lopes, C. |
Data: | Set-2010 |
Editora: | John Wiley & Sons Ltd |
Revista: | Journal of Peptide Science |
Resumo(s): | [Excerpt] Introduction: The reduction of an isolated double bond is not possible using electrochemical methods, however when the double bond is conjugated with an electron withdrawing group such as a carbonyl it becomes reducible in the accessible potential range [1]. For some years now we have been interested in the synthesis of dehydroamino acid derivatives and in using these compounds as substrates in several types of reactions [2]. As part of this work we have been studying the electrochemical behaviour of dehydroamino acid derivatives. Although there are many reports concerning the chemical reduction of α,β-dehydroamino acids, [3] to the best of our knowledge the electrochemical reduction of β,β-disubstituted dehydroamino acids has not yet been described. Since dehydroamino acids can be considered activated alkenes we decided to study the electrochemical reduction of β,β-diaryldehydroalanines and study the photophysical properties of some of the saturated amino acids prepared and compare them with those of the corresponding β,β-diaryldehydroalanines. [...] |
Tipo: | Resumo em ata de conferência |
Descrição: | Proceedings of the 31st European Peptide Symposium Michal Lebl, Morten Meldal, Knud J. Jensen, Thomas Hoeg-Jensen (Editors) European Peptide Society, 2010 |
URI: | https://hdl.handle.net/1822/72967 |
ISSN: | 1075-2617 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDQuim - Comunicações e Proceedings |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Proceedings electrochemistry.pdf | 253,34 kB | Adobe PDF | Ver/Abrir |