Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/74813

TítuloOrange thyme: phytochemical profiling, in vitro bioactivities of extracts and potential health benefits
Autor(es)Silva, Amélia M.
Félix, Luís M.
Teixeira, Isabel
Martins-Gomes, Carlos
Schäfer, Judith
Souto, Eliana B.
Santos, Dario J.
Bunzel, Mirko
Nunes, Fernando M.
Palavras-chaveOrange thyme
Phenolic composition
Antioxidant activity
Anti-proliferative
Anti-inflammatory activity
Aqueous extract
Hydroethanolic extract
Radical scavenging activities
Apigenin (PubChem CID: 5280443)
Eriodictyol (Pubchem CID 440735)
Luteolin (PubChem CID: 5280445)
Rosmarinic acid (PubChem CID: 5281792)
Salvianolic acid I (Pubchem CID 10459878)
Salvianolic acid K (Pubchem CID 10482829)
Data30-Dez-2021
EditoraElsevier
RevistaFood Chemistry: X
CitaçãoSilva, Amélia M.; Félix, Luís M.; Teixeira, Isabel; Martins-Gomes, Carlos; Schäfer, Judith; Souto, Eliana B.; Santos, Dario J.; Bunzel, Mirko; Nunes, Fernando M., Orange thyme: phytochemical profiling, in vitro bioactivities of extracts and potential health benefits. Food Chemistry: X, 12(100171), 2021
Resumo(s)Orange thyme (Thymus fragrantissimus) is becoming widely used in food as a condiment and herbal tea, nevertheless its chemical composition and potential bioactivities are largely unknown. Thus the objective of this work is to obtain a detailed phytochemical profile of T. fragrantissimus by exhaustive ethanolic extraction and by aqueous decoction mimicking its consumption. Extracts showed high content in rosmarinic acid, luteolin-O-hexuronide and eriodictyol-O-hexuronide; these were the main phenolic compounds present in orange thyme accounting for 85% of the total phenolic compounds. Orange thyme extracts presented high scavenging activity against nitric oxide and superoxide radicals. Both extracts presented significant inhibitory effect of tyrosinase activity and moderate anti-acetylcholinesterase activity. Both extracts showed a good in vitro anti-inflammatory activity and a weak anti-proliferative/cytotoxic activity against Caco-2 and HepG2 cell lines supporting its safe use. Orange thyme is a very good source of bioactive compounds with potential use in different food and nutraceutical industries.
TipoArtigo
URIhttps://hdl.handle.net/1822/74813
DOI10.1016/j.fochx.2021.100171
ISSN2590-1575
Versão da editorahttps://www.sciencedirect.com/journal/food-chemistry-x
Arbitragem científicayes
AcessoAcesso aberto
Aparece nas coleções:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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