Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/81887

TítuloSystems biology's role in leveraging microalgal biomass potential: Current status and future perspectives
Autor(es)Cunha, Emanuel
Sousa, Vítor
Geada, Pedro
Teixeira, J. A.
Vicente, A. A.
Dias, Oscar
Palavras-chaveMicroalgae
Upstream processing
Environmental factors
Systems biology
Genome-scale metabolic model
Data2023
EditoraElsevier Science BV
RevistaAlgal Research
CitaçãoCunha, E., Sousa, V., Geada, P., Teixeira, J. A., Vicente, A. A., & Dias, O. (2023, January). Systems biology's role in leveraging microalgal biomass potential: Current status and future perspectives. Algal Research. Elsevier BV. http://doi.org/10.1016/j.algal.2022.102963
Resumo(s)Microalgae are an eco-friendly and alternative source of several compounds that can be applied in numerous biotechnological branches such as cosmetics, food, or pharmaceutical industries. However, the commercialization of products from microalgae has still some drawbacks, among which it is possible to highlight the low biomass and compounds' productivities at industrial level. The common strategies to improve the process cost-effectiveness of microalgae cultivation are essentially based on optimising nutrient needs and several environmental factors (e.g., temperature, light intensity, salinity) that impact both their growth and biochemical composition. In this regard, genome-scale metabolic (GSM) models allow understanding the metabolic processes that lead to a final phenotype since they contain all known pathways, reactions, and metabolites of the organism, based on genomic information, available literature, and experimental data. This review provides an overview of the most important factors that need to be considered in microalgae cultivation, providing strategies to improve process cost-effectiveness. Particular emphasis will be given to the in silico-guided optimization as a real alternative, using GSM models to enhance the production of defined compounds and biomass.
TipoArtigo
URIhttps://hdl.handle.net/1822/81887
DOI10.1016/j.algal.2022.102963
ISSN2211-9264
Versão da editorahttps://www.sciencedirect.com/science/article/pii/S2211926422003344
Arbitragem científicayes
AcessoAcesso aberto
Aparece nas coleções:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
document_56005_1.pdf1,86 MBAdobe PDFVer/Abrir

Este trabalho está licenciado sob uma Licença Creative Commons Creative Commons

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID