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https://hdl.handle.net/1822/85459
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Campo DC | Valor | Idioma |
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dc.contributor.author | Fernandes, Ticiana | por |
dc.contributor.author | Osório, Carolina | por |
dc.contributor.author | Sousa, Maria João | por |
dc.contributor.author | Franco-Duarte, Ricardo | por |
dc.date.accessioned | 2023-07-10T13:16:53Z | - |
dc.date.available | 2023-07-10T13:16:53Z | - |
dc.date.issued | 2023-01-31 | - |
dc.identifier.citation | Fernandes, T.; Osório, C.; Sousa, M.J.; Franco-Duarte, R. Contributions of Adaptive Laboratory Evolution towards the Enhancement of the Biotechnological Potential of Non-Conventional Yeast Species. J. Fungi 2023, 9, 186. https://doi.org/10.3390/jof9020186 | por |
dc.identifier.uri | https://hdl.handle.net/1822/85459 | - |
dc.description.abstract | Changes in biological properties over several generations, induced by controlling shortterm evolutionary processes in the laboratory through selective pressure, and whole-genome re-sequencing, help determine the genetic basis of microorganism’s adaptive laboratory evolution (ALE). Due to the versatility of this technique and the imminent urgency for alternatives to petroleum-based strategies, ALE has been actively conducted for several yeasts, primarily using the conventional species Saccharomyces cerevisiae, but also non-conventional yeasts. As a hot topic at the moment since genetically modified organisms are a debatable subject and a global consensus on their employment has not yet been attained, a panoply of new studies employing ALE approaches have emerged and many different applications have been exploited in this context. In the present review, we gathered, for the first time, relevant studies showing the ALE of non-conventional yeast species towards their biotechnological improvement, cataloging them according to the aim of the study, and comparing them considering the species used, the outcome of the experiment, and the employed methodology. This review sheds light on the applicability of ALE as a powerful tool to enhance species features and improve their performance in biotechnology, with emphasis on the non-conventional yeast species, as an alternative or in combination with genome editing approaches. | por |
dc.description.sponsorship | This work was supported by the UID/BIA/04050/2013 (POCI-01-0145-FEDER-007569) and UID/BIA/04050/2019 strategic programs and the project PTDC/BIA-MIC/32059/2017, which is funded by national funds through the FCT-Fundação para a Ciência e Tecnologia and by the ERDF-European Regional Development Fund through the COMPETE2020–Programa Operacional Competitividade e Internacionalização (POCI) and Sistema de Apoio à Investigação Científica e Tecnológica (SAICT). T.F. was supported by Fellowship 2021.04595.BD from Fundação para a Ciência e Tecnologia, Portugal. | por |
dc.language.iso | eng | por |
dc.publisher | Multidisciplinary Digital Publishing Institute | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FBIA%2F04050%2F2013/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FBIA%2F04050%2F2019/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FBIA-MIC%2F32059%2F2017/PT | por |
dc.rights | openAccess | por |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | por |
dc.subject | Non-Saccharomyces | por |
dc.subject | Non-conventional yeast species | por |
dc.subject | Adaptation | por |
dc.subject | Evolution | por |
dc.subject | Biotechnology | por |
dc.subject | Yeasts | por |
dc.title | Contributions of adaptive laboratory evolution towards the enhancement of the biotechnological potential of non-conventional yeast species | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.mdpi.com/2309-608X/9/2/186 | por |
oaire.citationStartPage | 1 | por |
oaire.citationEndPage | 18 | por |
oaire.citationIssue | 2 | por |
oaire.citationVolume | 9 | por |
dc.date.updated | 2023-02-24T14:09:17Z | - |
dc.identifier.eissn | 2309-608X | - |
dc.identifier.doi | 10.3390/jof9020186 | por |
dc.subject.fos | Ciências Naturais::Ciências Biológicas | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Journal of Fungi | por |
oaire.version | VoR | por |
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jof-09-00186-v2.pdf | 654,24 kB | Adobe PDF | Ver/Abrir |
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