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https://hdl.handle.net/1822/31671
Título: | The use of bacteriophages for P. aeruginosa biofilm control |
Autor(es): | Pires, Diana Sillankorva, Sanna Azeredo, Joana |
Palavras-chave: | Adhesion Biomechanics Cellular biophysics Drugs Isolation technology Microorganisms Pseudomonas aeruginosa Adherence Bacteriophages Bacterium Biofilm control Human epithelium Isolation Low antibiotic susceptibility Lytic phages Multidrug resistant strains Nosocomial infections Opportunistic pathogen Planktonic cells Virulence factors Virulent biofllms Antibiotics Biomedical optical imaging Hospitals Immune system Microorganisms Optical buffering Strain Bacteriophages Biofilms Control P. aeruginosa |
Data: | 2011 |
Citação: | Pires, Diana; Sillankorva, Sanna; Azeredo, Joana, The use of bacteriophages for P. aeruginosa biofilm control. ENBENG 2011 - 1st Portuguese Meeting in Bioengineering. Lisbon, Portugal, 1-4 March, 1-42011. . ISBN: 978-1-4577-0522-9 |
Resumo(s): | Pseudomonas aeruginosa is a relevant opportunistic pathogen frequently associated with several nosocomial infections and, worryingly, this bacterium shows a low antibiotic susceptibility. One of its virulence factors is related with the ability to adhere to surfaces and also human epithelium and form virulent biofllms. This work describes the isolation and characterization of lytic phages capable to infect antibiotic resistant P. aeruginosa strains. It is also described herein the potential of the new isolated phages for planktonic cells and biofilm control. According to the results of this work, the isolated phages showed different spectra of activity and most of them were efficient even against P. aeruginosa multidrug resistant strains. Furthermore, the biofilm infection assays revealed that phages can be a good strategy to combat virulent biofilms achieving significant reductions in the number of biofilm cells. |
Tipo: | Artigo em ata de conferência |
URI: | https://hdl.handle.net/1822/31671 |
ISBN: | 978-1-4577-0522-9 |
DOI: | 10.1109/ENBENG.2011.6026045 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Artigos em Livros de Atas / Papers in Proceedings |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_18157_1.pdf | 614,87 kB | Adobe PDF | Ver/Abrir |