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https://hdl.handle.net/1822/7893
Título: | Performance of 3 methods for quality control for gynecologic cytology diagnoses |
Autor(es): | Utagawa, Maria Lúcia Shirata, Neuza Kasumi Ferraz, Maria da Gloria Mattosinho de Castro Loreto, Celso di Dall’ Agnol, Miria Longatto Filho, Adhemar |
Palavras-chave: | Cytologic technique Papanicolaou smear Quality control |
Data: | 2008 |
Editora: | Karger Publishers |
Revista: | Acta Cytologica |
Resumo(s): | ObjectiveTo evaluate performance and viability of internal quality control QC) strategies in a public health laboratory of the state of Sao Paulo.Study DesignA retrospective study was per formed with 3 QC strategies to improve internal cytologic diagnoses: morphologic guided-list criteria (MGLC), 100% rapid-rescreening (100% RR) of negative slides ("turret" method) and 10% rescreening (10% R) of negative slides. Cases were examined at Adolfo Lutz Institute, Sao Paulo, Brazil, from 2002 to 2004. Histopathologic results, when available, were considered gold standard; cytologic consensus diagnosis was by 2 pathologists when histologic results were unavailable.ResultsMGLC selected 20.7% samples with cytologic atypias, 10% R selected 0.6% and RR selected 2.5%. Cytologic/histologic initial concordance was 57.4%, low-grade squamous intraepithelial lesion false negative rate was 34.9% and high-grade squamous intraepithelial lesion false negative rate was 12.2%. After diagnosis, consensus concordance was 97.2%.ConclusionThe 100% RR and 10% R QC strategies detected more false negative cases in liquid-based cytology than in conventional Pap smears. The 100% RR strategy reduced the false negative results and allowed evaluation of individual staff performance. The 10% R strategy did not offer significant results. We concluded that association of MGLC and 100% RR strategies might improve cytologic diagnostic quality. |
Tipo: | Artigo |
Descrição: | Prova tipográfica (In Press) |
URI: | https://hdl.handle.net/1822/7893 |
DOI: | 10.1159/000325549 |
ISSN: | 0001-5547 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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AC-03414-07_PTA2.pdf | 487,66 kB | Adobe PDF | Ver/Abrir |