Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/12931
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Martins, Albino | - |
dc.contributor.author | Silva, Marta L. Alves da | - |
dc.contributor.author | Faria, Susana | - |
dc.contributor.author | Marques, A. P. | - |
dc.contributor.author | Reis, R. L. | - |
dc.contributor.author | Neves, N. M. | - |
dc.date.accessioned | 2011-07-20T15:03:20Z | - |
dc.date.available | 2011-07-20T15:03:20Z | - |
dc.date.issued | 2011-07-01 | - |
dc.identifier.issn | 1616-5187 | por |
dc.identifier.uri | https://hdl.handle.net/1822/12931 | - |
dc.description.abstract | A specially designed electroconductive collector enables the electrospinning of P-NFM composed of areas of parallel/uniaxially aligned fibers and areas of random/orthogonal nanofiber distribution. The biological relevance of P-NFM is demonstrated using hBMSCs as an autologous cell source. The structures induce cell orientation along the uniaxially aligned fibers, mainly during earlier culturing periods under basal and osteogenic differentiation conditions. The microtopography of the P-NFM also controls the deposition of mineralized extracellular matrix along the pre-defined fiber direction. Genotypic characterization confirms the successful differentiation into the osteogenic lineage. | por |
dc.description.sponsorship | European Integrated Project GENOSTEM (LSH-STREP-CT-2003-503161); European Network of Excellence EXPERTISSUES (NMP3-CT-2004-500283); Portuguese Foundation for Science and Technology for the project Naturally Nano (POCI/EME/58982/2004) and the PhD grant SFRH/BD/24382/2005) | por |
dc.language.iso | eng | por |
dc.publisher | Wiley | por |
dc.rights | openAccess | por |
dc.subject | Biodegradable | por |
dc.subject | Electrospinning | por |
dc.subject | Mesenchymal stem cells | por |
dc.subject | Patterned nanofiber meshes | por |
dc.subject | Tissue engineering | por |
dc.title | The influence of patterned nanofiber meshes on human mesenchymal stem cell osteogenesis | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://onlinelibrary.wiley.com/doi/10.1002/mabi.201100012/abstract | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 978 | por |
oaire.citationEndPage | 987 | por |
oaire.citationIssue | 7 | por |
oaire.citationTitle | Macromolecular Bioscience | por |
oaire.citationVolume | 11 | por |
dc.identifier.doi | 10.1002/mabi.201100012 | por |
dc.identifier.pmid | 21485007 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Macromolecular Bioscience | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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The Influence of Patterned Nanofiber Meshes on Human Mesenchymal Stem Cells Osteogenesis - Martins A, ..., Neves NM.pdf | AMartins_Macromolecular Bioscience 2011 | 965,06 kB | Adobe PDF | Ver/Abrir |