Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/25932
Título: | Potential of human γD-crystallin for hair damage repair: insights into the mechanical properties and biocompatibility |
Autor(es): | Ribeiro, Artur J. Matamá, Maria Teresa Cruz, Célia F. Gomes, Andreia C Paulo, Artur Cavaco |
Palavras-chave: | Greek key motif Hair treatment Human crystallin Mechanical properties improvement Over bleached hair |
Data: | 2013 |
Editora: | Wiley |
Revista: | International Journal of Cosmetic Science |
Resumo(s): | The objective of this work was to develop a new strategy to physically ‘repair’ chemically damaged hair. Hence the human eye γD-crystallin, a protein from the superfamily characterized structurally by the Greek key motif, was studied. The human γD-crystallin was chosen based on the ability of proteins belonging to this superfamily to be involved in the coating of specific structures. Two crystallins were used on the study, the wild type (Protein Data Bank ID: 1HK0) and the mutant protein. The mutant form was intended to induce a strong and quick protein polymerization as well to have new possible points of anchorage to hair. L'objectif de ce travail était de développer une nouvelle stratégie pour physiquement “réparer” les cheveux chimiquement endommagés. La protéine humaine γD-cristalline, une protéine de la superfamille caractérisée structurellement par le motif clé grecque, a été étudiée. Le γD-cristallin humain a été choisi en fonction de la capacité des protéines appartenant à cette superfamille d'être impliquées dans le revêtement des structures spécifiques. Deux cristallins ont été utilisés dans l'étude, le type sauvage (Protein Data Bank ID: 1HK0) et la protéine mutante. La forme mutante était destinée à induire une polymérisation de la protéine, forte et rapide ainsi d'avoir de nouveaux points d'ancrage possibles aux cheveux. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/25932 |
DOI: | 10.1111/ics.12065 |
ISSN: | 1468-2494 |
Versão da editora: | http://dx.doi.org/10.1111/ics.12065 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series CBMA - Artigos/Papers DBio - Artigos/Papers |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2013 Potential of human γD-crystallin for hair damage repair- insights into the mechanical properties and biocompatibility.pdf | Potential of human γD-crystallin for hair damage repair: insights into the mechanical properties and biocompatibility | 663,03 kB | Adobe PDF | Ver/Abrir |