Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/33676
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Scapulatempo-Neto, Cristovam | por |
dc.contributor.author | Fregnani, José Humberto T. G. | por |
dc.contributor.author | Campacci, Natália | por |
dc.contributor.author | Resende, Júlio Cesar Possati | por |
dc.contributor.author | Longatto Filho, Adhemar | por |
dc.date.accessioned | 2015-02-06T16:45:41Z | - |
dc.date.available | 2015-02-06T16:45:41Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0001-5547 | por |
dc.identifier.uri | https://hdl.handle.net/1822/33676 | - |
dc.description.abstract | OBJECTIVE: This study sought to ascertain the significance of augmented high-grade squamous intraepithelial lesion (HSIL) detection by Pap test using both conventional smear and liquid-based cytology (LBC) in a high-risk population. STUDY DESIGN: We conducted a direct-to-vial study to compare the diagnostic performance of Pap smear versus LBC in a high-risk population of women referred for colposcopy at a gynecologic ambulatory clinic at the Barretos Cancer Hospital in Brazil during 2011. RESULTS: The detection of both low-grade squamous intraepithelial lesions (LSILs) and HSILs was significantly greater (p = 0.04 and p = 0.033, respectively) in the LBC arm [84 LSIL cases (5.7%) and 148 HSIL cases (10.1%)] than in the conventional smear arm [66 LSIL cases (4.1%) and 126 HSIL cases (7.9%)]; however, no differences were found for invasive squamous carcinoma or adenocarcinoma (p = 0.678). Of 3,071 women who were examined cytologically (1,604 conventional preparations and 1,467 LBC) and colposcopically, biopsies were available for 279 conventional preparations (17.6%) and 325 LBC preparations (22.2%). No significant differences were found between the methods with respect to diagnostic performance. CONCLUSION: LBC was significantly superior to conventional smears for the detection of LSILs and HSILs, but these results did not influence biopsy confirmation. Both methods showed similar performances with high positive predictive values but very low sensitivities. | por |
dc.description.sponsorship | This study was partially supported by BD, which donated the SurePath vials and Papanicolaou staining reagents. The study design, statistical analyses, interpretation of the results and manuscript development were carried out by the team of the Barretos Cancer Hospital with no involvement from BD. | por |
dc.language.iso | eng | por |
dc.publisher | Karger AG | por |
dc.rights | openAccess | por |
dc.subject | Pap test | por |
dc.subject | Cytological screening | por |
dc.subject | Liquid-based cytology | por |
dc.subject | Pap test | por |
dc.subject | SurePath TM | por |
dc.subject | Cytopathology | por |
dc.subject | SurePath™ | por |
dc.title | The significance of augmentedhigh-grade squamous intraepithelial lesion detection on pap test examination: partial results from the RODEO study team | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.karger.com/Article/Pdf/351789 | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 489 | por |
oaire.citationEndPage | 494 | por |
oaire.citationIssue | 5 | por |
oaire.citationTitle | Acta Cytologica | por |
oaire.citationVolume | 57 | por |
dc.date.updated | 2015-01-30T16:12:52Z | - |
dc.identifier.doi | 10.1159/000351789 | por |
dc.identifier.pmid | 24135251 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Acta Cytologica | por |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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scapulatempo c_acta cytologica 2013.pdf | 169,4 kB | Adobe PDF | Ver/Abrir |