Hypoxia is a typical feature of the tumor microenvironment, one of the most critical factors affecting cell behavior and tumor progression. However, the lack of tumor models able to precisely emulate natural brain tumor tissue has&#...

Oral treatment of colon diseases with the CRISPR/Cas9 system has been hampered by the lack of a safe and efficient delivery platform. Overexpressed CD98 plays a crucial role in the progression of ulcerative colitis (UC) and...

Oral administration is the most preferred approach for treating colon diseases, and in situ vaccination has emerged as a promising cancer therapeutic strategy. However, the lack of effective drug delivery platforms hampered the application of i...

Silk is called the “Queen” of “fibers” due to its eco-friendly nature, robust mechanical properties, biocompatibility, heat conductivity, durability, luster, and tunable biodegradability. Consequently, silk has been widely used to fabricate matrices&#x...