Chitosan-based nanoparticles prepared by template polymerization

Abstract

INTRODUCTION: Chitosan (CS) /poly(acrylic acid) (PAA) nanoparticles (NPs) have recently been obtained by template polymerization1. In this technique, the NPs are produced upon polymerization of an acrylic monomer next to the chitosan backbone. Due to the electrostatic interaction, the negatively charged acrylic monomers align along the chitosan molecules. These physic interactions leads to self-assembled particles. The molecular weight and deacetylation degree of chitosan affect the solubility, size, and stability of the particles. (...)