Extending the reservoir of bla IMP-5: the emerging pathogen Acinetobacter bereziniae

doi:10.2217/fmb.15.88

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/38723

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Campo DC	Valor	Idioma
dc.contributor.author	Grosso, Filipa	por
dc.contributor.author	Silva, Liliana	por
dc.contributor.author	Sousa, C.	por
dc.contributor.author	Ramos, Helena	por
dc.contributor.author	Quinteira, Sandra	por
dc.contributor.author	Peixe, Luísa	por
dc.date.accessioned	2015-12-07T11:27:52Z	-
dc.date.available	2015-12-07T11:27:52Z	-
dc.date.issued	2015	-
dc.identifier.citation	Grosso, Filipa; Silva, Liliana; Sousa, C.; Ramos, Helena; Quinteira, Sandra; Peixe, Luísa, Extending the reservoir of bla IMP-5: the emerging pathogen Acinetobacter bereziniae. Future Microbiology, 10(10), 1609-1613, 2015	por
dc.identifier.issn	1746-0913	por
dc.identifier.uri	https://hdl.handle.net/1822/38723	-
dc.description.abstract	Acinetobacter bereziniae clinical relevance is starting to be recognized; however, very few descriptions of its carbapenem resistance currently exist. Here we characterize two carbapenem-resistant A. bereziniae isolates. Materials & methods: Isolates were obtained from environmental and clinical samples. Carbapenemases were searched by phenotypic, biochemical and PCR assays. Clonality was studied by ApaI-PFGE and genetic location for carbapenemase genes were assessed by I-CeuI and S1 hybridizations. Results: Isolates were not clonally related but both produced the exclusively Portuguese IMP-5, with the clinical isolate also producing an OXA-58. The carbapenemase genes were plasmid located. Conclusion: Our results emphasize the role of non-baumannii Acinetobacter species as important reservoirs of clinically relevant resistance genes that could also contribute to their emergence as nosocomial pathogens	por
dc.description.sponsorship	This work was funded by FEDER funds through the Operational Programme for Competitiveness Factors – COMPETE and by National Funds through FCT – Foundation for Science and Technology under the project Pest-C/EQB/LA0006/2013. L Silva and F Grosso were supported by grants from FCT (SFRH/BD/88028/2012 and SFRH/BPD/95556/2013, respectively). C Sousa was funded by an FCT contract CIENCIA2008. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript.	por
dc.language.iso	eng	por
dc.publisher	Future Medicine	por
dc.relation	info:eu-repo/grantAgreement/FCT/COMPETE/132972/PT	por
dc.relation	SFRH/BD/88028/2012	por
dc.relation	SFRH/BPD/95556/2013	por
dc.rights	openAccess	por
dc.subject	Acinetobacter bereziniae	por
dc.subject	carbapenem resistance	por
dc.subject	IMP-5	por
dc.subject	integron	por
dc.subject	metallo--lactamase	por
dc.subject	oxacillinase	por
dc.subject	metallo-ß-lactamase	por
dc.title	Extending the reservoir of bla IMP-5: the emerging pathogen Acinetobacter bereziniae	por
dc.type	article	-
dc.peerreviewed	yes	por
dc.relation.publisherversion	http://www.futuremedicine.com/loi/fmb	por
dc.comments	CEB23418	por
sdum.publicationstatus	published	por
oaire.citationStartPage	1609	por
oaire.citationEndPage	1613	por
oaire.citationIssue	10	por
oaire.citationConferencePlace	United Kingdom	-
oaire.citationTitle	Future Microbiology	por
oaire.citationVolume	10	por
dc.date.updated	2015-12-06T16:15:57Z	-
dc.identifier.eissn	1746-0921	-
dc.identifier.doi	10.2217/fmb.15.88	por
dc.identifier.pmid	26439605	por
dc.subject.wos	Science & Technology	por
sdum.journal	Future Microbiology	por
Aparece nas coleções:	CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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