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https://hdl.handle.net/1822/43295
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Campo DC | Valor | Idioma |
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dc.contributor.author | Diender, Martijn | por |
dc.contributor.author | Pereira, Ricardo A. G. | por |
dc.contributor.author | Wessels, Hans J. C. T. | por |
dc.contributor.author | Stams, Alfons Johannes Maria | por |
dc.contributor.author | Sousa, Diana Z | por |
dc.date.accessioned | 2016-12-07T09:27:47Z | - |
dc.date.available | 2016-12-07T09:27:47Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Diender, Martijn; Pereira, Ricardo A. G.; Wessels, Hans J. C. T.; Stams, A. J. M.; Sousa, Diana Z, Proteomic analysis of the hydrogen and carbon monoxide metabolism of Methanothermobacter marburgensis. Frontiers in Microbiology, 7(1049), 1-10, 2016 | por |
dc.identifier.issn | 1664-302X | por |
dc.identifier.uri | https://hdl.handle.net/1822/43295 | - |
dc.description.abstract | Hydrogenotrophic methanogenic archaea are efficient H2 utilizers, but only a few are known to be able to utilize CO. Methanothermobacter thermoautotrophicus is one of the hydrogenotrophic methanogens able to grow on CO, albeit about 100 times slower than on H2 + CO2. In this study we show that the hydrogenotrophic methanogen Methanothermobacter marburgensis, is able to perform methanogenic growth on H2/CO2/CO and on CO as a sole substrate. To gain further insight in its carboxydotrophic metabolism, the proteome of M. marburgensis, grown on H2/CO2 and H2/CO2/CO, was analysed. Cultures grown with H2/CO2/CO showed relative higher abundance of enzymes involved in the reductive acetyl-CoA pathway and proteins involved in redox metabolism. The data suggest that the strong reducing capacity of CO negatively affects hydrogenotrophic methanogenesis, making growth on CO as a sole substrate difficult for this type of methanogens. M. marburgensis appears to partly deal with this by upregulating co-factor regenerating reactions and activating additional pathways allowing for formation of other products, like acetate. | por |
dc.description.sponsorship | Research of AS is supported by an ERC grant (project 323009) and a Gravitation grant (project024.002.002)of the Netherlands Ministry of Education, Culture and Science and the Netherlands Science Foundation (NWO). | por |
dc.language.iso | eng | por |
dc.publisher | Frontiers Media | por |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/323009/EU | por |
dc.rights | openAccess | por |
dc.subject | syngas | por |
dc.subject | methanogenesis | por |
dc.subject | CODH | por |
dc.subject | Reductive acetyl-CoA pathway | por |
dc.subject | Methanothermobacter thermoautotrophicus | por |
dc.title | Proteomic analysis of the hydrogen and carbon monoxide metabolism of Methanothermobacter marburgensis | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://journal.frontiersin.org/journal/microbiology | por |
dc.comments | CEB40045 | por |
sdum.publicationstatus | info:eu-repo/semantics/publishedVersion | por |
oaire.citationStartPage | 1 | por |
oaire.citationEndPage | 10 | por |
oaire.citationIssue | 1049 | por |
oaire.citationTitle | Frontiers in Microbiology | por |
oaire.citationVolume | 7 | por |
dc.date.updated | 2016-12-02T00:25:34Z | - |
dc.identifier.eissn | 1664-302X | - |
dc.identifier.doi | 10.3389/fmicb.2016.01049 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Frontiers in Microbiology | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_40045_1.pdf | 773,01 kB | Adobe PDF | Ver/Abrir |