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dc.contributor.authorAndrade, R.por
dc.contributor.authorVasta, S.por
dc.contributor.authorPereira, R.por
dc.contributor.authorPereira, H.por
dc.contributor.authorPapalia, R.por
dc.contributor.authorKarahan, M.por
dc.contributor.authorOliveira, J. M.por
dc.contributor.authorReis, R. L.por
dc.contributor.authorEspregueira-Mendes, Joãopor
dc.identifier.citationAndrade R., Vasta S., Pereira R., Pereira H., Papalia R., Karahan M., Oliveira J. M., Reis R. L., Espregueira-Mendes J. Knee donor-site morbidity in mosaicplasty - A systematic review, Journal of Experimental Orthopaedics, doi:10.1186/s40634-016-0066-0, 2016por
dc.description.abstractBackground: Mosaicplasty has been associated with good short- to long-term results. Nevertheless, the osteochondral harvesting is restricted to the donor-site area available and it may lead to significant donor-site morbidity. Purpose: Provide an overview of donor-site morbidity associated with harvesting of osteochondral plugs from the knee joint in mosaicplasty procedure. Methods: Comprehensive search using Pubmed, Cochrane Library, SPORTDiscus and CINAHL databases was carried out through 10th October of 2016. As inclusion criteria, all English-language studies that assessed the knee donor- site morbidity after mosaicplasty were accepted. The outcomes were the description and rate of knee donor-site morbidity, sampleâ s and cartilage defectâ s characterization and mosaicplasty-related features. Correlation between mosaicplasty features and rate of morbidity was performed. The methodological and reporting quality were assessed according to Colemanâ s methodology score. Results: Twenty-one studies were included, comprising a total of 1726 patients, with 1473 and 268 knee and ankle cartilage defects were included. The defect size ranged from 0.85 cm2 to 4.9 cm2 and most commonly 3 or less plugs (averaging 2.9 to 9.4 mm) were used. Donor-site for osteochondral harvesting included margins of the femoral trochlea (condyles), intercondylar notch, patellofemoral joint and upper tibio-fibular joint. Mean donor-site morbidity was 5.9 % and 19.6 % for knee and ankle mosaicplasty procedures, respectively. Concerning knee-to-knee mosaicplasty procedures, the most common donor-site morbidity complaints were patellofemoral disturbances (22 %) and crepitation (31 %), and in knee-to-ankle procedures there was a clear tendency for pain or instability during daily living or sports activities (44 %), followed by patellofemoral disturbances, knee stiffness and persistent pain (13 % each). There was no significant correlation between rate of donor-site morbidity and size of the defect, number and size of the plugs (p > 0.05). Conclusions: Osteochondral harvesting in mosaicplasty often results in considerable donor-site morbidity. The donor-site morbidity for knee-to-ankle (16.9 %) was greater than knee-to-knee (5.9 %) mosaicplasty procedures, without any significant correlation between rate of donor-site morbidity and size of the defect, number and size of the plugs. Lack or imcomplete of donor-site morbidity reporting within the mosaicplasty studies is a concern that should be addressed in future studies.por
dc.subjectSystematic reviewpor
dc.subjectArticular cartilage lesionspor
dc.subjectDonor-site morbiditypor
dc.titleKnee donor-site morbidity in mosaicplasty - A systematic reviewpor
oaire.citationTitleJournal of Experimental Orthopaedicspor
sdum.journalJournal of Experimental Orthopaedicspor
Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals
ICVS - Artigos em revistas internacionais / Papers in international journals

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