1. Universidade do Minho
  2. Escola de Engenharia | School of Engineering
  3. Centro de Engenharia Biológica | Centre of Biological Engineering
  4. CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series
Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/44740

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Campo DCValorIdioma
dc.contributor.authorTobaldini-Valerio, Fláviapor
dc.contributor.authorBonfim-Mendonça, P. S.por
dc.contributor.authorRosseto, H. C.por
dc.contributor.authorBruschi, M. L.por
dc.contributor.authorHenriques, Marianapor
dc.contributor.authorNegri, Melyssapor
dc.contributor.authorSilva, Sónia Carinapor
dc.contributor.authorSvidzinski, Terezinhapor
dc.date.accessioned2017-02-13T15:40:54Z-
dc.date.available2017-02-13T15:40:54Z-
dc.date.issued2016-08-
dc.identifier.citationTobaldini-Valerio, Flávia; Bonfim-Mendonça, Patricia S.; Rosseto, Helen C.; Bruschi, Marcos L.; Henriques, Mariana; Negri, Melyssa; Silva, Sónia Carina; Svidzinski, Terezinha I. E., Propolis: a potential natural product to fight Candida species infections. Future Microbiology, 11(8), 1035-1046, 2016por
dc.identifier.issn1746-0913por
dc.identifier.urihttps://hdl.handle.net/1822/44740-
dc.description.abstractAim: To evaluate the effect of propolis against Candida species planktonic cells and its counterpart's biofilms. Materials & methods: The MIC values, time-kill curves and filamentation form inhibition were determined in Candida planktonic cells. The effect of propolis on Candida biofilms was assessed through quantification of CFUs. Results: MIC values, ranging from 220 to 880 µg/ml, demonstrated higher efficiency on C. albicans and C. parapsilosis than on C. tropicalis cells. In addition, propolis was able to prevent Candida species biofilm's formation and eradicate their mature biofilms, coupled with a significant reduction on C. tropicalis and C. albicans filamentation. Conclusion: Propolis is an inhibitor of Candida virulence factors and represents an innovative alternative to fight candidiasis.por
dc.description.sponsorshipThe authors thank Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Conselho Nacional de Desenvolvimento Científico e Tecnológico (Cnpq) and Fundação Araucária for the financial support received. Flávia Tobaldini-Valerio acknowledges the financial support of CAPES – Proc. 9469/14-1. The authors also thank FCT for the Strategic Project of the UID/BIO/04469/2013 unit, FCT and European Union funds (FEDER/COMPETE) for the project RECI/BBBEBI/0179/2012 (FCOMP-01-0124-FEDER-027462). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.por
dc.language.isoengpor
dc.publisherFuture Medicinepor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147337/PT-
dc.relationinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/126270/PT-
dc.relationinfo:eu-repo/grantAgreement/FCT/COMPETE/126270/PT-
dc.rightsopenAccesspor
dc.subjectCandida speciespor
dc.subjectBiofilmpor
dc.subjectPropolis extractpor
dc.subjectVirulence factorspor
dc.titlePropolis: a potential natural product to fight Candida species infectionspor
dc.typearticle-
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.futuremedicine.com/loi/fmbpor
dc.commentsCEB41157por
oaire.citationStartPage1035por
oaire.citationEndPage1046por
oaire.citationIssue8por
oaire.citationConferencePlaceUnited Kingdom-
oaire.citationTitleFuture Microbiologypor
oaire.citationVolume11por
dc.date.updated2017-02-04T17:17:47Z-
dc.identifier.eissn1746-0921por
dc.identifier.doi10.2217/fmb-2015-0016por
dc.identifier.pmid27501739por
dc.subject.wosScience & Technologypor
sdum.journalFuture Microbiologypor
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