Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/44743
Título: | Dietary restriction and nutrient balance in aging |
Autor(es): | Leão, Cecília Santos, Júlia Margarida Raposo Monteiro Correia, Fernanda Leitão Sousa, Maria João |
Data: | 2016 |
Editora: | Hindawi Publishing Corporation |
Revista: | Oxidative Medicine and Cellular Longevity |
Citação: | Santos, J., Leitão-Correia, F., Sousa, M. J., & Leão, C. (2016). Dietary Restriction and Nutrient Balance in Aging. Oxidative Medicine and Cellular Longevity, 2016. doi: 10.1155/2016/4010357 |
Resumo(s): | Dietary regimens that favour reduced calorie intake delay aging and age-associated diseases. New evidences revealed that nutritional balance of dietary components without food restriction increases lifespan. Particular nutrients as several nitrogen sources, proteins, amino acid, and ammonium are implicated in life and healthspan regulation in different model organisms from yeast to mammals. Aging and dietary restriction interact through partially overlapping mechanisms in the activation of the conserved nutrient-signalling pathways, mainly the insulin/insulin-like growth factor (IIS) and the Target Of Rapamycin (TOR). The specific nutrients of dietary regimens, their balance, and how they interact with different genes and pathways are currently being uncovered. Taking into account that dietary regimes can largely influence overall human health and changes in risk factors such as cholesterol level and blood pressure, these new findings are of great importance to fully comprehend the interplay between diet and humans health. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/44743 |
DOI: | 10.1155/2016/4010357 |
ISSN: | 1942-0900 |
Versão da editora: | http://www.hindawi.com/journals/omcl/ |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals DBio - Artigos/Papers |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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santos et al_final.pdf | 1,45 MB | Adobe PDF | Ver/Abrir |