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TitleBioinformatics tools for exploring the SUMO gene network
Author(s)Castro, Pedro Humberto
Santos, Miguel Ângelo
Magalhães, Alexandre Papadopoulos
Tavares, R. M.
Azevedo, Herlânder Anselmo Queirós Pereira
Computational Biology
Gene Regulatory Networks
Small Ubiquitin-Related Modifier Proteins
Issue date2016
CitationCastro, P. H., Santos, M. Â., Magalhães, A. P., Tavares, R. M., & Azevedo, H. (2016). Bioinformatics Tools for Exploring the SUMO Gene Network. In Plant Proteostasis (pp. 285-301). Humana Press, New York, NY
Abstract(s)Plant sumoylation research has seen significant advances in recent years, particularly since high-throughput proteomics strategies have enabled the discovery of hundreds of potential SUMO targets and interactors of SUMO pathway components. In the present chapter, we introduce the SUMO Gene Network (SGN), a curated assembly of Arabidopsis thaliana genes that have been functionally associated with sumoylation, from SUMO pathway components to targets and interactors. The enclosed tutorial helps interpret and manage these datasets, and details bioinformatics tools that can be used for in silico-based hypothesis generation. The latter include tools for sumoylation site prediction, comparative genomics, and gene network analysis.
DescriptionBook: Plant Proteostasis ; ISBN: 978-1-4939-3757-8 / 978-1-4939-3759-2; uncorrected proof
AccessRestricted access (Author)
Appears in Collections:CBFP - Artigos/Papers
DBio - Artigos/Papers

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