Neurodevelopment impact of CO2-pneumoperitoneum in neonates: experimental study in a rat model

doi:10.1016/j.jss.2017.09.014

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/57897

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Campo DC	Valor	Idioma
dc.contributor.author	Miranda, Alice Augusta Macedo	por
dc.contributor.author	Roque, Susana	por
dc.contributor.author	Pêgo, José M.	por
dc.contributor.author	Correia-Pinto, Jorge	por
dc.date.accessioned	2019-01-08T10:43:22Z	-
dc.date.available	2021-02-01T07:00:54Z	-
dc.date.issued	2018-01	-
dc.identifier.citation	Miranda, A., Roque, S., Pêgo, J. M., & Correia-Pinto, J. (2018). Neurodevelopment impact of CO 2-pneumoperitoneum in neonates: experimental study in a rat model. Journal of Surgical Research, 221, 293-303	por
dc.identifier.issn	0022-4804	-
dc.identifier.uri	https://hdl.handle.net/1822/57897	-
dc.description.abstract	Laparoscopy is becoming more common in neonates. However, concerns remain about the impact of the carbon-dioxide (CO2)-insufflation over the neonatal brain. We aim to evaluate the peripheral (serum) and central (cerebrospinal fluid [CSF]) cytokine response after neonatal CO2-pneumoperitoneum and its impact over neurodevelopmental milestones acquisition and long-term behavioral outcomes.	por
dc.description.sponsorship	FEDER, through the Competitiveness Factors Operational Programme (COMPETE), and by National funds, through the Foundation for Science and Technology (FCT), under the project POCI-01-0145-FEDER-007038; and by the project NORTE-01-0145-FEDER-000013, supported by the Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (FEDER). A Miranda and S. Roque were supported by FCT grants (SFRH/BD/52059/2012) and (SFRH/BPD/72710/2010), respectively. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The authors would like to thank Karl Storz GmbH for equipment and technical support	por
dc.language.iso	eng	por
dc.publisher	Elsevier 1	por
dc.relation	info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F52059%2F2012/PT	-
dc.relation	info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F72710%2F2010/PT	-
dc.rights	openAccess	por
dc.subject	Animals	eng
dc.subject	Carbon Dioxide	eng
dc.subject	Cytokines	eng
dc.subject	Female	eng
dc.subject	Inflammation	eng
dc.subject	Neurodevelopmental Disorders	eng
dc.subject	Pneumoperitoneum, Artificial	eng
dc.subject	Pregnancy	eng
dc.subject	Rats, Sprague-Dawley	eng
dc.subject	Stress, Physiological	eng
dc.subject	Laparoscopy	eng
dc.subject	Carbon-dioxide pneumoperitoneum	eng
dc.subject	Neurodevelopment	eng
dc.subject	Cytokine	eng
dc.subject	Interleukin	eng
dc.title	Neurodevelopment impact of CO2-pneumoperitoneum in neonates: experimental study in a rat model	eng
dc.type	article	por
dc.peerreviewed	yes	por
dc.relation.publisherversion	https://www.sciencedirect.com/science/article/pii/S002248041730611X	por
oaire.citationStartPage	293	por
oaire.citationEndPage	303	por
oaire.citationVolume	221	por
dc.identifier.eissn	1095-8673	-
dc.identifier.doi	10.1016/j.jss.2017.09.014	por
dc.identifier.pmid	29229141	por
dc.subject.fos	Ciências Médicas::Medicina Básica	por
dc.description.publicationversion	info:eu-repo/semantics/publishedVersion	por
dc.subject.wos	Science & Technology	por
sdum.journal	Journal of Surgical Research	por
Aparece nas coleções:	ICVS - Artigos em revistas internacionais / Papers in international journals