Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/57923
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Pereira, Ricardo | por |
dc.contributor.author | Leite, Eduarda | por |
dc.contributor.author | Raimundo, Joana | por |
dc.contributor.author | Guilherme, Sofia | por |
dc.contributor.author | Puga, Sónia Andreia Silva | por |
dc.contributor.author | Pinto-Ribeiro, Filipa | por |
dc.contributor.author | Santos, Maria Ana | por |
dc.contributor.author | Canário, João | por |
dc.contributor.author | Almeida, Armando | por |
dc.contributor.author | Pacheco, Mário | por |
dc.contributor.author | Pereira, Patrícia | por |
dc.date.accessioned | 2019-01-08T15:13:40Z | - |
dc.date.available | 2021-10-01T06:00:31Z | - |
dc.date.issued | 2018-09 | - |
dc.identifier.citation | Pereira, R., Leite, E., Raimundo, J., Guilherme, S., et. al. (2018). Metals (loids) targeting fish eyes and brain in a contaminated estuary-Uncovering neurosensory (un) susceptibility through bioaccumulation, antioxidant and morphometric profiles. Marine environmental research, 140, 403-411 | por |
dc.identifier.issn | 0141-1136 | por |
dc.identifier.uri | https://hdl.handle.net/1822/57923 | - |
dc.description.abstract | This study examined the susceptibility of fish (Liza aurata) eyes and brain to metals(loids) contamination under realistic exposure conditions. A multidimensional approach was applied to fish caught at a chronically contaminated site (BAR) and at a reference site of the Tagus estuary (Portugal), which comprised metals(loids) accumulation in eyes and brain together with a battery of enzymatic and non-enzymatic antioxidants, as well as brain morphometry (i.e. cell density). Trace element levels in the blood, gills, liver and kidney allowed interpretations on their preferential pathway(s) to the eyes and brain. Metals(loids) accumulation pointed out the elevated vulnerability of the fish eyes at BAR, probably related with the direct waterborne uptake. Pb uptake in L. aurata eyes could be associated both with water and indirect pathways. At the most contaminated site, metals(loids) were on the basis of pro-oxidant conditions in the ocular tissues, while no indication of toxicity was recorded in the brain. Overall, the results disclosed a differential bioaccumulation among fish organs, suggesting that, in the L. aurata population studied, metal organotropism underlie the lower susceptibility of the brain comparing to the eyes. However, mechanisms remain little understood and further work is needed. | por |
dc.description.sponsorship | CESAM (UID/AMB/50017 - POCI-01-0145-FEDER-007638), to FCT/MCTES through national funds (PIDDAC), and the co-funding by the FEDER, within the PT2020 Partnership Agreement and Compete 2020, and due for the Research Project NEUTOXMER project (FCT-PTDC/AAGREC/2488/2012) (which provided a research grant to Sónia Puga) | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876/147273/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/128281/PT | - |
dc.relation | info:eu-repo/grantAgreement/FCT/COMPETE/128281/PT | - |
dc.rights | openAccess | por |
dc.subject | Neurosensory toxicity | por |
dc.subject | Antioxidant defenses | por |
dc.subject | Brain ste Antioxidant defenses Brain stereology Wild fish Estuariesreology | por |
dc.subject | Wild fish | por |
dc.subject | Estuaries | por |
dc.subject | Brain stereology | por |
dc.title | Metals(loids) targeting fish eyes and brain in a contaminated estuary - Uncovering neurosensory (un)susceptibility through bioaccumulation, antioxidant and morphometric profiles | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S014111361830134X | por |
oaire.citationStartPage | 403 | por |
oaire.citationEndPage | 411 | por |
oaire.citationVolume | 140 | por |
dc.identifier.eissn | 0141-1136 | - |
dc.identifier.doi | 10.1016/j.marenvres.2018.07.001 | por |
dc.identifier.pmid | 30054132 | por |
dc.subject.fos | Ciências Médicas::Medicina Básica | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Marine Environmental Research | por |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Pereira R. Mar Environ Res.pdf | 1,11 MB | Adobe PDF | Ver/Abrir |