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https://hdl.handle.net/1822/58062| Título: | Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis |
| Autor(es): | Ruesen, Carolien Chaidir, Lidya van Laarhoven, Arjan Dian, Sofiati Ganiem, Ahmad Rizal Guimarães, Hanna Nebenzahl Huynen, Martijn A. Alisjahbana, Bachti Dutilh, Bas E. van Crevel, Reinout |
| Palavras-chave: | Computational Biology Genomics Humans Indonesia Mycobacterium tuberculosis Phenotype Phylogeny Polymorphism, Single Nucleotide Tuberculosis, Meningeal Tuberculosis, Pulmonary Genes, Bacterial Genetic Variation Genome, Bacterial Pulmonary tuberculosis Tuberculous meningitis Whole genome sequencing Homoplasy |
| Data: | 2018 |
| Editora: | Springer Nature |
| Revista: | BMC Genomics |
| Citação: | Ruesen, C., Chaidir, L., van Laarhoven, A., Dian, S., Ganiem, A. R., et. al. (2018). Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis. BMC genomics, 19(1), 122 |
| Resumo(s): | Meningitis is the most severe manifestation of tuberculosis. It is largely unknown why some people develop pulmonary TB (PTB) and others TB meningitis (TBM); we examined if the genetic background of infecting M. tuberculosis strains may be relevant. |
| Tipo: | Artigo |
| URI: | https://hdl.handle.net/1822/58062 |
| DOI: | 10.1186/s12864-018-4498-z |
| ISSN: | 1471-2164 |
| e-ISSN: | 1471-2164 |
| Versão da editora: | https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4498-z |
| Arbitragem científica: | yes |
| Acesso: | Acesso aberto |
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| LARGE-~1.PDF | 1,26 MB | Adobe PDF | Ver/Abrir |
