Please use this identifier to cite or link to this item: https://hdl.handle.net/1822/59271

TitleEffect of poling state of piezoelectric poly(vinylidene fluoride) films on C2C12 myoblast differentiation for skeletal muscle tissue engineering
Author(s)Ribeiro, Sylvie
Ribeiro, Clarisse
Gomes, A. C.
Lanceros-Méndez, S.
Issue date9-Apr-2017
CitationRibeiro, Sylvie; Ribeiro, Clarisse; Gomes, A. C.; Lanceros-Méndez, S., Effect of poling state of piezoelectric poly(vinylidene fluoride) films on C2C12 myoblast differentiation for skeletal muscle tissue engineering. Materiais 2017. Aveiro, Portugal, 9-12 April, 44, 2017.
Abstract(s)[Excerpt] Skeletal muscles, comprising between 40-45% of an adult human body mass, are responsible for generating voluntary movement, postural support, breathing and locomotion. Severe injuries resulting in a muscle mass loss can lead to extensive and irreversible loss of muscle function [1]. In this sense, tissue engineering (TE) and regenerative medicine are growing fields of interest due to promising results in regenerating tissue functions [1]. Adhesion, proliferation and differentiation of specific cells can be promoted and/or improved by the use of active materials. In particular, piezoelectric materials allow incorporating electrical and mechanical stimuli to the cells. This is a recent paradigm with large potential in TE applications [2]. Further, many body tissues are subjected to varying mechanical loads, such as muscle [3], and the charge surface can stimulate cell response. In this sense, the use of polymer based electroactive materials capable to mimic mechanical and electrical biological cues emerged as a novel approach for TE applications. [...]
TypeAbstract
URIhttps://hdl.handle.net/1822/59271
Publisher versionhttp://materiais2017.web.ua.pt/programme.htm
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Resumos em Livros de Atas / Abstracts in Proceedings

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