The resting-brain of obsessive-compulsive disorder

doi:10.1016/j.pscychresns.2019.06.008

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/62408

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Campo DC	Valor	Idioma
dc.contributor.author	Moreira, Pedro Silva	por
dc.contributor.author	Marques, Paulo	por
dc.contributor.author	Magalhães, Ricardo	por
dc.contributor.author	Esteves, Madalena	por
dc.contributor.author	Sousa, Nuno	por
dc.contributor.author	Soares, José Miguel	por
dc.contributor.author	Morgado, Pedro	por
dc.date.accessioned	2019-11-26T13:14:10Z	-
dc.date.available	2020-08-30T06:00:14Z	-
dc.date.issued	2019-08-30	-
dc.identifier.issn	0925-4927	-
dc.identifier.uri	https://hdl.handle.net/1822/62408	-
dc.description.abstract	Obsessive–compulsive disorder (OCD) is one of the most debilitating psychiatric conditions, having a dramatic impact on patients’ daily living. In this work, we aimed to explore resting-state functional connectivity in OCD patients, using an independent component analysis. Eighty individuals (40 patients and 40 healthy controls) performed a resting state fMRI protocol. OCD patients displayed reduced functional connectivity (FC) in visual and sensorimotor networks. In addition, patients displayed decreased FC between sensory networks and increased FC between default-mode and cerebellar networks.	por
dc.description.sponsorship	Pedro Silva Moreira was supported by the FCT fellowship grant with the number PDE/BDE/113601/2015 from the PhD-iHES program; Paulo Marques was funded by the Fundação Calouste Gulbenkian (Contract grant number: P-139977; project “Better mental health during ageing based on temporal prediction of individual brain ageing trajectories (TEMPO)”); Ricardo Magalhães was supported by the FCT fellowship grant with the number PDE/BDE/113604/2015 from the PhD-iHES program; Madalena Esteves was supported by the FCT fellowship grant with the number SFRH/BD/52291/2013 from the PhDOC program. The present work was supported by SwitchBox-FP7-HEALTH2010-grant 259772-2 and co-financed by the Portuguese North Regional Operational Program (ON.2 – O Novo Norte) under the National Strategic Reference Framework (QREN), through the European Regional Development Fund (FEDER).	por
dc.language.iso	eng	por
dc.publisher	Elsevier	por
dc.relation	info:eu-repo/grantAgreement/FCT/PD/PD%2FBD%2F52291%2F2013/PT	por
dc.rights	openAccess	por
dc.subject	Obsessive-compulsive disorder	por
dc.subject	Resting-state networks	por
dc.subject	FMRI	por
dc.title	The resting-brain of obsessive-compulsive disorder	por
dc.type	article	por
dc.peerreviewed	yes	por
oaire.citationStartPage	38	por
oaire.citationEndPage	41	por
oaire.citationVolume	290	por
dc.identifier.doi	10.1016/j.pscychresns.2019.06.008	por
dc.identifier.pmid	31279239	por
dc.subject.wos	Science & Technology	por
sdum.journal	Psychiatry Research: Neuroimaging	por
Aparece nas coleções:	ICVS - Artigos em revistas internacionais / Papers in international journals