Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/64930
Título: | Nanomedicines for the delivery of antimicrobial peptides (AMPs) |
Autor(es): | Teixeira, Maria C. Carbone, Claudia Sousa, Maria C. Espina, Marta Garcia, Maria L. Sanchez-Lopez, Elena Souto, Eliana B. |
Palavras-chave: | antimicrobial peptides bacterial and virus infections coronavirus antimicrobial resistance nanomaterials nanomedicine |
Data: | 20-Mar-2020 |
Editora: | MDPI |
Revista: | Nanomaterials |
Citação: | Teixeira, Maria C.; Carbone, Claudia; Sousa, Maria C.; Espina, Marta; Garcia, Maria L.; Sanchez-Lopez, Elena; Souto, Eliana, Nanomedicines for the Delivery of Antimicrobial Peptides (AMPs). Nanomaterials, 10(3), 560, 2020 |
Resumo(s): | Microbial infections are still among the major public health concerns since several yeasts and fungi, and other pathogenic microorganisms, are responsible for continuous growth of infections and drug resistance against bacteria. Antimicrobial resistance rate is fostering the need to develop new strategies against drug-resistant superbugs. Antimicrobial peptides (AMPs) are small peptide-based molecules of 5–100 amino acids in length, with potent and broad-spectrum antimicrobial properties. They are part of the innate immune system, which can represent a minimal risk of resistance development. These characteristics contribute to the description of these molecules as promising new molecules in the development of new antimicrobial drugs. However, efforts in developing new medicines have not resulted in any decrease of drug resistance yet. Thus, a technological approach on improving existing drugs is gaining special interest. Nanomedicine provides easy access to innovative carriers, which ultimately enable the design and development of targeted delivery systems of the most efficient drugs with increased efficacy and reduced toxicity. Based on performance, successful experiments, and considerable market prospects, nanotechnology will undoubtedly lead a breakthrough in biomedical field also for infectious diseases, as there are several nanotechnological approaches that exhibit important roles in restoring antibiotic activity against resistant bacteria. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/64930 |
DOI: | 10.3390/nano10030560 |
e-ISSN: | 2079-4991 |
Versão da editora: | http://www.mdpi.com/journal/nanomaterials |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_53595_1.pdf | 1,45 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons