Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/75216
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Braga, Adelaide | por |
dc.contributor.author | Gomes, Daniela | por |
dc.contributor.author | Costa, João Manuel Rainha | por |
dc.contributor.author | Amorim, Cláudia | por |
dc.contributor.author | Cardoso, Beatriz | por |
dc.contributor.author | Gudiña, Eduardo José | por |
dc.contributor.author | Silvério, Sara Isabel Cruz | por |
dc.contributor.author | Rodrigues, Joana Lúcia Lima Correia | por |
dc.contributor.author | Rodrigues, L. R. | por |
dc.date.accessioned | 2022-01-05T10:49:17Z | - |
dc.date.available | 2022-01-05T10:49:17Z | - |
dc.date.issued | 2021-12-16 | - |
dc.identifier.citation | Braga, Adelaide; Gomes, Daniela; , J. Rainha; Amorim, Cláudia; Cardoso, B.; Gudiña, Eduardo J.; Silvério, Sara C.; Rodrigues, Joana L.; Rodrigues, Lígia R., Zymomonas mobilis as an emerging biotechnological chassis for the production of industrially relevant compounds. Bioresources and Bioprocessing, 8(128), 2021 | por |
dc.identifier.issn | 2197-4365 | por |
dc.identifier.uri | https://hdl.handle.net/1822/75216 | - |
dc.description.abstract | Zymomonas mobilis is a well-recognized ethanologenic bacterium with outstanding characteristics which make it a promising platform for the biotechnological production of relevant building blocks and fine chemicals compounds. In the last years, research has been focused on the physiological, genetic, and metabolic engineering strategies aiming at expanding Z. mobilis ability to metabolize lignocellulosic substrates toward biofuel production. With the expansion of the Z. mobilis molecular and computational modeling toolbox, the potential of this bacterium as a cell factory has been thoroughly explored. The number of genomic, transcriptomic, proteomic, and fluxomic data that is becoming available for this bacterium has increased. For this reason, in the forthcoming years, systems biology is expected to continue driving the improvement of Z. mobilis for current and emergent biotechnological applications. While the existing molecular toolbox allowed the creation of stable Z. mobilis strains with improved traits for pinpointed biotechnological applications, the development of new and more flexible tools is crucial to boost the engineering capabilities of this bacterium. Novel genetic toolkits based on the CRISPR-Cas9 system and recombineering have been recently used for the metabolic engineering of Z. mobilis. However, they are mostly at the proof-of-concept stage and need to be further improved. | por |
dc.description.sponsorship | This review is supported by Portuguese Foundation for Science and Technol ogy (FCT) under the scope of the strategic funding of UIDB/04469/2020 unit and the project FoSynBio (POCI-01-0145-FEDER-029549). SFRH/BD/138325/2018, SFRH/BD/132324/2017, SFRH/BD/04433/2020, Fundação para a Ciência e a Tecnologia, UMINHO/BPD/4/2019. | por |
dc.language.iso | eng | por |
dc.publisher | SpringerOpen | por |
dc.relation | UIDB/04469/2020 | por |
dc.relation | SFRH/BD/138325/2018 | por |
dc.relation | SFRH/BD/132324/2017 | por |
dc.relation | SFRH/BD/04433/2020 | por |
dc.relation | UMINHO/BPD/4/2019 | por |
dc.rights | openAccess | por |
dc.subject | Bioproducts | por |
dc.subject | Industrial chassis | por |
dc.subject | Metabolic Engineering | por |
dc.subject | Synthetic biology | por |
dc.subject | Zymomonas mobilis | por |
dc.title | Zymomonas mobilis as an emerging biotechnological chassis for the production of industrially relevant compounds | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://bioresourcesbioprocessing.springeropen.com/ | por |
dc.comments | CEB55116 | por |
oaire.citationIssue | 128 | por |
oaire.citationVolume | 8 | por |
dc.date.updated | 2021-12-30T17:39:44Z | - |
dc.identifier.doi | 10.1186/s40643-021-00483-2 | por |
dc.subject.fos | Ciências Naturais::Ciências Biológicas | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | Bioresources and Bioprocessing | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_55116_1.pdf | 1,7 MB | Adobe PDF | Ver/Abrir |