Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/89964
Título: | Mechanical stimulation devices for mechanobiology studies: a market, literature, and patents review |
Autor(es): | Fonseca, Francisca Rocha Melo Carvalho, Óscar Samuel Novais Gasik, M. Miranda, G. Silva, Filipe Samuel |
Palavras-chave: | Biomaterials Polymers Actuators Mechanical stress Mechanotransduction |
Data: | Abr-2023 |
Editora: | Springer |
Revista: | Bio-Design and Manufacturing |
Citação: | Melo-Fonseca, F., Carvalho, O., Gasik, M. et al. Mechanical stimulation devices for mechanobiology studies: a market, literature, and patents review. Bio-des. Manuf. 6, 340–371 (2023). https://doi.org/10.1007/s42242-023-00232-8 |
Resumo(s): | Significant advancements in various research and technological fields have contributed to remarkable findings on the physiological dynamics of the human body. Tomore closely mimic the complex physiological environment, research has moved from two-dimensional (2D) culture systems to more sophisticated three-dimensional (3D) dynamic cultures. Unlike bioreactors or microfluidic-based culture models, cells are typically seeded on polymeric substrates or incorporated into 3D constructs which are mechanically stimulated to investigate cell response to mechanical stresses, such as tensile or compressive. This review focuses on the working principles of mechanical stimulation devices currently available on the market or custom-built by research groups or protected by patents and highlights the main features still open to improvement. These are the features which could be focused on to perform, in the future, more reliable and accurate mechanobiology studies. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/89964 |
DOI: | 10.1007/s42242-023-00232-8 |
ISSN: | 2096-5524 |
e-ISSN: | 2522-8552 |
Versão da editora: | https://link.springer.com/article/10.1007/s42242-023-00232-8 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito autor |
Aparece nas coleções: | CMEMS - Artigos em revistas internacionais/Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Mechanical stimulation devices for mechanobiology studies-a market, literature, and patents review.pdf Acesso restrito! | 5,73 MB | Adobe PDF | Ver/Abrir |