Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/90678
Título: | Engineered bacteriophages to target amyloyd-β in the brain |
Autor(es): | Martins, Ivone M. |
Data: | 5-Jun-2018 |
Editora: | Faculdade de Ciências de Lisboa |
Citação: | Martins, Ivone M., Invited Lecture: Engineered bacteriophages to target amyloyd- in the brain. BioISI Research Seminar, 2018. |
Resumo(s): | Amyloid-beta (AB) is a prime suspect to cause Alzheimer’s disease (AD). An accumulation of AB in the brain leads to its aggregation into still-soluble oligomeric and fibrillar clusters. In AD-mouse models, these AB oligomers and fibrils impair synaptic function and memory formation. However, a diagnostic tool to detect AB oligomers/fibrils selectively in the brain is currently not available. In this seminar an overview of a project, aiming at developing a cost-effective and safe bacteriophage-based tool to selectively diagnose AB oligomers and fibrils during the early stage of AD, will be presented. |
Tipo: | Palestra |
URI: | https://hdl.handle.net/1822/90678 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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FC_Seminar_June2018.pdf | 4,27 MB | Adobe PDF | Ver/Abrir |