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https://hdl.handle.net/1822/91837
Título: | Long-term and short-term preservation strategies for tissue engineering and regenerative medicine products: state of the art and emerging trends |
Autor(es): | Freitas-Ribeiro, Sara Reis, R. L. Pirraco, Rogério P. |
Palavras-chave: | Dry state preservation Hypothermic preservation Normothermic preservation Slow freezing Vitrification |
Data: | Set-2022 |
Editora: | Oxford University Press |
Revista: | Pnas nexus |
Citação: | Freitas-Ribeiro S., Reis R. L., Pirraco R. P. Long-term and short-term preservation strategies for tissue engineering and regenerative medicine products: state of the art and emerging trends, PNAS nexus, Vol. 1, Issue 4, pp. 1-15, doi:10.1093/pnasnexus/pgac212, 2022. |
Resumo(s): | There is an ever-growing need of human tissues and organs for transplantation. However, the availability of such tissues and organs is insufficient by a large margin, which is a huge medical and societal problem. Tissue engineering and regenerative medicine (TERM) represent potential solutions to this issue and have therefore been attracting increased interest from researchers and clinicians alike. But the successful large-scale clinical deployment of TERM products critically depends on the development of efficient preservation methodologies. The existing preservation approaches such as slow freezing, vitrification, dry state preservation, and hypothermic and normothermic storage all have issues that somehow limit the biomedical applications of TERM products. In this review, the principles and application of these approaches will be summarized, highlighting their advantages and limitations in the context of TERM products preservation. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/91837 |
DOI: | 10.1093/pnasnexus/pgac212 |
ISSN: | 2752-6542 |
Versão da editora: | https://academic.oup.com/pnasnexus/article/1/4/pgac212/6731796 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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20914-pgac212.pdf | 4,75 MB | Adobe PDF | Ver/Abrir |