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dc.contributor.authorAbreu, Ana S.-
dc.contributor.authorSilva, Natália O.-
dc.contributor.authorFerreira, Paula M. T.-
dc.contributor.authorQueiroz, Maria João R. P.-
dc.date.accessioned2005-06-09T08:52:12Z-
dc.date.available2005-06-09T08:52:12Z-
dc.date.issued2003-
dc.identifier.citationAbreu, A. S., Silva, N. O., Ferreira, P. M. T., & Queiroz, M.-J. R. P. (2003, April). Synthesis and intramolecular cyclization of novel β,β-bis-(benzo[b]thienyl)dehydroalanine derivatives. Tetrahedron Letters. Elsevier BV. http://doi.org/10.1016/s0040-4039(03)00564-1eng
dc.identifier.issn0040-4039por
dc.identifier.urihttps://hdl.handle.net/1822/2057-
dc.description.abstractThe methyl ester of tert-butyloxycarbonyl-beta,beta-dibromodehydroalanine was obtained in a one pot procedure from bis-(N-tert-butyloxycarbonyl)dehydroalanine. The former was reacted with several boronic benzo[b]thiophene acids under Suzuki cross coupling conditions, to give new beta,beta-bis-(benzo[b]thienyl)dehydroalanines in high yields. These compounds were cyclized to pyrrole derivatives by treatment with Pd(OAc)2 and Cu(OAc)2 in DMF.eng
dc.description.sponsorshipWe wish to thank the Foundation for Science and Technology (Portugal) for financial support through project POCTI/1999/QUI/32689 (also support of N.O. Silva) and through SFRH/BD/4709/2001, PhD financial support of A.S. Abreu.por
dc.language.isoengeng
dc.publisherElsevier 1eng
dc.relationinfo:eu-repo/grantAgreement/FCT/POCI/POCTI%2FQUI%2F32689%2F2000/PT-
dc.relationinfo:eu-repo/grantAgreement/FCT/POCTI/SFRH%2FBD%2F4709%2F2001/PT-
dc.rightsopenAccesseng
dc.subjectBeta,beta-dibromodehydroalanineeng
dc.subjectBeta,beta-bis-(benzo[b]thienyldehydroalanineeng
dc.subjectSuzuki cross couplingeng
dc.subjectPyrrole derivativeseng
dc.subjectβ,β-bis-(benzo[b]thienyl) dehydroalaninepor
dc.subjectβ,β-dibromodehydroalaninepor
dc.titleSynthesis and intramolecular cyclization of novel beta,beta-bis(benzo[b]thienyl)dehydroalanine derivativeseng
dc.typearticleeng
dc.peerreviewedyeseng
oaire.citationStartPage3377por
oaire.citationEndPage3379por
oaire.citationIssue16por
oaire.citationVolume44por
dc.identifier.doi10.1016/S0040-4039(03)00564-1por
dc.subject.wosScience & Technologypor
sdum.journalTetrahedron Letterspor
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