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https://hdl.handle.net/1822/28182
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Campo DC | Valor | Idioma |
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dc.contributor.author | Leite, Álvaro J. | - |
dc.contributor.author | Sher, Praveen | - |
dc.contributor.author | Mano, J. F. | - |
dc.date.accessioned | 2014-02-27T15:49:47Z | - |
dc.date.available | 2014-02-27T15:49:47Z | - |
dc.date.issued | 2014-04 | - |
dc.identifier.issn | 0167-577X | por |
dc.identifier.uri | https://hdl.handle.net/1822/28182 | - |
dc.description | "Available online 24 January 2014" | por |
dc.description.abstract | We investigated the interaction of natural derived macromolecular multilayers with calcium and phosphate ions entirely processed using the layer-by-layer (LbL) technique. A nanostructured multilayer component, with 5 or 10 bilayers, was first produced using weak polyelectrolyte biopolymers, chitosan and chondroitin sulfate. This was followed by sequential passing of solutions containing Ca2+andPO43−over the multilayers. QCM-D, SEM and EDX results conferred the formation of calcium phosphate (CaP) over the polyelectrolyte multilayers. Initiation of precipitation was observed earlier in the 10 bilayers coating than in the 5 bilayers one. These results indicate the potential of multilayers to trap ions, as a biomimetic approach that can be used to induce CaP precipitation. This could enable the preparation of more performant bioactive composite biomaterials for orthopedic applications, including in bone tissue engineering. | por |
dc.description.sponsorship | This work was supported by the Portuguese Foundation for Science and Technology (FCT), through the doctoral Grant SFRH/BD/73174/2010 of Alvaro J. Leite and postdoctoral grant SFRH/BPD/489948/2008 of Praveen Sher. | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.rights | restrictedAccess | por |
dc.subject | Multilayer structure | por |
dc.subject | Biomimetic | por |
dc.subject | Biomaterials | por |
dc.subject | Nanocomposites | por |
dc.title | Chitosan/chondroitin sulfate multilayers as supports for calcium phosphate biomineralization | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://dx.doi.org/10.1016/j.matlet.2014.01.099 | por |
dc.comments | http://www.3bs.uminho.pt/node/17903 | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 62 | por |
oaire.citationEndPage | 65 | por |
oaire.citationTitle | Materials letters | por |
oaire.citationVolume | 121 | por |
dc.date.updated | 2014-02-26T17:37:26Z | - |
dc.identifier.doi | 10.1016/j.matlet.2014.01.099 | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | Materials letters | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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17903-10.1016:j.matlet.2014.01.099.pdf Acesso restrito! | 1,36 MB | Adobe PDF | Ver/Abrir |