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https://hdl.handle.net/1822/42483
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Campo DC | Valor | Idioma |
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dc.contributor.author | Barros, Alexandre António Antunes | por |
dc.contributor.author | Aroso, Ivo Manuel Ascensão | por |
dc.contributor.author | Silva, Tiago José Quinteiros Lopes Henriques | por |
dc.contributor.author | Mano, J. F. | por |
dc.contributor.author | Duarte, Ana Rita C. | por |
dc.contributor.author | Reis, R. L. | por |
dc.date.accessioned | 2016-09-07T11:13:45Z | - |
dc.date.issued | 2016-08 | - |
dc.identifier.citation | Barros A. A., Aroso I. M., Silva T. H., Mano J. F., Duarte A. R. C., Reis R. L. In vitro bioactivity studies of ceramic structures isolated from marine sponges, Biomedical Materials, Issue 11, pp. 045004, doi:10.1088/1748-6041/11/4/045004, 2016 | por |
dc.identifier.issn | 1748-605X | por |
dc.identifier.uri | https://hdl.handle.net/1822/42483 | - |
dc.description.abstract | In this work, we focused on the potential of bioceramics from different marine spongesâ namely Petrosia ficiformis, Agelas oroides and Chondrosia reniformisâ for novel biomedical/industrial applications. The bioceramics from these sponges were obtained after calcination at 750 °C for 6 h in a furnace. The morphological characteristics were evaluated by scanning electron microscopy (SEM). The in vitro bioactivity of the bioceramics was evaluated in simulated body fluid (SBF) after 14 and 21 d. Observation of the bioceramics by SEM after immersion in SBF solution, coupled with spectroscopic elemental analysis (EDS), showed that the surface morphology was consistent with a calcium-phosphate (Ca/P) coating, similar to hydroxyapatite crystals (HA). Evaluation of the characteristic peaks of Ca/P crystals by Fourier transform infrared spectroscopy and x-ray diffraction further confirmed the existence of HA. Cytotoxicity studies were carried out with the different ceramics and these were compared with a commercially available Bioglass®. In vitro tests demonstrated that marine bioceramics from these sponges are non-cytotoxic and have the potential to be used as substitutes for synthetic Bioglass®. | por |
dc.description.sponsorship | FCT through grant EXP/QEQ-EPS/0745/2012, SWIMS—Subcritical Water Isolation of compounds from Marine Sponges. | por |
dc.description.sponsorship | European Union Seventh Framework Programme (FP7/2007–2013) under grant agreement numbers REGPOT-CT2012-316331-POLARIS and KBBE-2010–266033 (project SPECIAL) | por |
dc.description.sponsorship | North Portugal Regional Operational Programme (ON.2—O Novo Norte) under the National Strategic Reference Framework (NSRF) | por |
dc.description.sponsorship | European Research Council grant agreement ERC- 2012-ADG 20120216-321266 for project ComplexiTE | por |
dc.language.iso | eng | por |
dc.publisher | IOP Publishing | por |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/316331/EU | por |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/266033/EU | por |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/321266/EU | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/127219/PT | - |
dc.relation | info:eu-repo/grantAgreement/FCT/COMPETE/127219/PT | - |
dc.rights | restrictedAccess | por |
dc.subject | Marine sponge | por |
dc.subject | Bioactivity | por |
dc.subject | Hydroxyapatite | por |
dc.subject | Bioactive glass | por |
dc.subject | Bioceramics | por |
dc.title | In vitro bioactivity studies of ceramic structures isolated from marine sponges | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://iopscience.iop.org/article/10.1088/1748-6041/11/4/045004/meta;jsessionid=CB9B36AA8E86783180C59800E8CFF64F.c3.iopscience.cld.iop.org | por |
dc.comments | http://3bs.uminho.pt/node/18795 | por |
sdum.publicationstatus | info:eu-repo/semantics/publishedVersion | por |
oaire.citationStartPage | 045004(1) | por |
oaire.citationEndPage | 045004(11) | por |
oaire.citationIssue | 4 | por |
oaire.citationTitle | Biomedical Materials | por |
oaire.citationVolume | 11 | por |
dc.date.updated | 2016-09-05T15:49:07Z | - |
dc.identifier.doi | 10.1088/1748-6041/11/4/045004 | por |
dc.identifier.pmid | 27481449 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Biomedical Materials | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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18795-In vitro bioactivity studies of ceramic structures isolated from marine sponges.pdf Acesso restrito! | 1,27 MB | Adobe PDF | Ver/Abrir |