Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/47647
Título: | Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing |
Autor(es): | Felgueiras, Helena Prado Amorim, M. T. Pessoa de |
Palavras-chave: | Electrospun wound dressings Functionalization Antimicrobial peptides Collagen type I |
Data: | 14-Nov-2017 |
Editora: | Institute of Physics Publishing |
Revista: | IOP Conference Series: Materials Science and Engineering |
Resumo(s): | Modern wound dressings combine medical textiles with active compounds that stimulate wound healing while protecting against infection. Electrospun wound dressings have been extensively studied and the electrospinning technique recognized as an efficient approach for the production of nanoscale fibrous mats. The unique diverse function and architecture of antimicrobial peptides (AMPs) has attracted considerable attention as a tool for the design of new anti-infective drugs. Functionalizing electrospun wound dressings with these AMPs is nowadays being researched. In the present work, we explore these new systems by highlighting the most important characteristics of electropsun wound dressings, revealing the importance of AMPs to wound healing, and the methods available to functionalize the electrospun mats with these molecules. The combined therapeutic potential of collagen type I and these AMP functionalized dressings will be highlighted as well; the significance of these new strategies for the future of wound healing will be clarified. |
Tipo: | Artigo em ata de conferência |
URI: | https://hdl.handle.net/1822/47647 |
DOI: | 10.1088/1757-899X/254/6/062004 |
ISSN: | 1757-8981 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | DET/2C2T - Artigos em revistas internacionais com arbitragem científica |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2017 IOP Conf Ser Mater Sci Eng.pdf | 359,03 kB | Adobe PDF | Ver/Abrir |