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https://hdl.handle.net/1822/48498
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Campo DC | Valor | Idioma |
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dc.contributor.author | Silva, Rui | por |
dc.contributor.author | Aguiar, Tatiana Quinta | por |
dc.contributor.author | Oliveira, Rui | por |
dc.contributor.author | Domingues, Lucília | por |
dc.date.accessioned | 2017-12-21T12:54:10Z | - |
dc.date.available | 2017-12-21T12:54:10Z | - |
dc.date.issued | 2017-12-07 | - |
dc.identifier.citation | Silva, Rui; Aguiar, Tatiana Q.; Oliveira, Rui; Domingues, Lucília, Ashbya gossypii riboflavin overproducing strains are highly susceptible to light-induced oxidative DNA damage. Microbiotec'17 - Congress of Microbiology and Biotechnology 2017. No. O-25, Porto, Portugal, Dec 7-9, 61-61, 2017. | por |
dc.identifier.uri | https://hdl.handle.net/1822/48498 | - |
dc.description | Microbiotec'17 - Congress of Microbiology and Biotechnology 2017 | por |
dc.description.abstract | Background The overproduction of riboflavin by Ashbya gossypii, which is one of the most distinctive traits of this filamentous hemiascomycete, is triggered by oxidative stress [1]. In turn, riboflavin is a strong photosensitizer that upon irradiation with light has been shown to generate reactive oxygen species (ROS) and induce oxidative DNA damage in mammalian cells [2-3]. Envisioning a better understanding of this A. gossypii trait, here we investigated whether riboflavin overproduction is associated with increased DNA damage. [...] | por |
dc.description.sponsorship | Study supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684) (Post-Doc grant to T. Q. Aguiar), BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under the scope of Norte2020 - Programa Operacional Regional do Norte, Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124FEDER-027462) and PhD grant PD/BD/113812/2015 to R. Silva. | por |
dc.language.iso | eng | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876/147337/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/126270/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/COMPETE/126270/PT | por |
dc.relation | PD/BD/113812/2015 | por |
dc.rights | openAccess | por |
dc.title | Ashbya gossypii riboflavin overproducing strains are highly susceptible to light-induced oxidative DNA damage | por |
dc.type | conferenceAbstract | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.porto.ucp.pt/pt/microbiotec17 | por |
dc.comments | CEB47359 | por |
sdum.event.type | congress | por |
oaire.citationStartPage | 61 | por |
oaire.citationEndPage | 61 | por |
oaire.citationIssue | O-25 | - |
oaire.citationConferencePlace | Porto, Portugal | por |
dc.date.updated | 2017-12-19T15:30:28Z | - |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
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document_47359_1.pdf | 233,31 kB | Adobe PDF | Ver/Abrir |